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Production of the antimalarial drug precursor artemisinic acid in engineered yeast

Dae-Kyun Ro, Eric M. Paradise, Mario Ouellet, Karl J. Fisher, Karyn L. Newman, John M. Ndungu, Kimberly A. Ho, Rachel A. Eachus, Timothy S. Ham, James Kirby, Michelle C. Y. Chang, Sydnor T. Withers, Yoichiro Shiba, Richmond Sarpong and Jay D. Keasling

Nature 440, 940-943 (13 April 2006)

doi:10.1038/nature04640