Editorials

Towards better biosecurity p715

Slowly but surely, a key advisory committee is helping the scientific community act more responsibly when conducting and publishing biological research that could carry security risks.

doi:10.1038/440715a

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Shooting the messenger p716

The abolition of a science advisory board to the US government sends the wrong signal.

doi:10.1038/440716a

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Rightful owners p716

Research into anthropological artefacts must acknowledge claims of prior ownership.

doi:10.1038/440716b

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Research Highlights

Research highlights p718

doi:10.1038/440718a

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News

Further accusations rock Japanese RNA laboratory p720

Suspicion of fraud hangs over pioneering RNA work.

Ichiko Fuyuno

doi:10.1038/440720a

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Doubts over evolution block funding by Canadian agency p720

Study of 'intelligent design' refused funds.

Hannah Hoag

doi:10.1038/440720b

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Korean science powerhouse sends Nobel laureate packing p721

Clash of cultures means early return for physics prizewinner.

David Cyranoski

doi:10.1038/440721a

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Guinea experts cry foul on tribal exhibits p722

A new exhibition of Melanesian artefacts raises questions about how the pieces ended up in a Californian art museum. Rex Dalton investigates.

doi:10.1038/440722a

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Energy secretary ditches science advisers p725

Independent panel dismissed after nearly 30 years.

Geoff Brumfiel

doi:10.1038/440725a

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Wellcome Trust fuelled bid to save British science treasure p725

Private donors finance return of Hooke's manuscript.

Michael Hopkin

doi:10.1038/440725b

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From the front lines p726

As the H5N1 flu virus continues to sweep across the globe, researchers in some of the countries affected describe in their own words the political and scientific challenges that they face.

doi:10.1038/440726a

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Sidelines p727

doi:10.1038/440727a

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News in brief p728

doi:10.1038/440728a

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News Features

Cell biology: The story of i p730

Multicellular creatures can be battlegrounds for competing populations of cells. Claire Ainsworth learns how this way of looking at an individual is feeding into immunology and cancer biology.

doi:10.1038/440730a

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Climate science: A sinking feeling p734

The floods are getting worse in Tuvalu. As scientists argue over climate change and struggle to measure rising seas, Samir S. Patel meets the locals of this tiny island nation.

doi:10.1038/440734a

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Business

Biologist aims to ease the pain for entrepreneurs p738

Biotech start-ups face a struggle to survive. Virginia Gewin reports on an initiative that brings cash and experience together to improve their chances.

doi:10.1038/440738a

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In brief p739

doi:10.1038/440739a

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Market watch p739

doi:10.1038/440739b

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Correspondence

Avoiding hazards of best-guess climate scenarios p740

Arnulf Grubler, Brian O'Neill and Detlef van Vuuren

doi:10.1038/440740a

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Physician–scientists are needed now more than ever p740

Ajit Varki, Edward Holmes, Tadataka Yamada, Peter Agre and Sydney Brenner

doi:10.1038/440740b

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India's concern about both security and sea research p740

Satish Singh

doi:10.1038/440740c

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Tools needed to navigate landscape of the genome p740

Mark Gerstein

doi:10.1038/440740d

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Commentary

Feline friend or potential foe? p741

What role do cats play in the epidemiology of H5N1 avian flu virus? We don't yet have all the answers, but it's time to consider new precautions, argue Thijs Kuiken, Albert Osterhaus, Peter Roeder and their colleagues.

doi:10.1038/440741a

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Books and Arts

The making of geology p743

In the late eighteenth century, ideas about the age of rocks and fossils gave rise to a new science.

Stephen Moorbath reviews Bursting the Limits of Time: The Reconstruction of Geohistory in the Age of Revolution by Martin J. S. Rudwick

doi:10.1038/440743a

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Men of astronomy p744

J. D. Fernie reviews Revolutionaries of the Cosmos: The Astro-Physicists by Ian Glass

doi:10.1038/440744a

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The puzzle of cooperation p744

Andrew M. Colman reviews Moral Sentiments and Material Interests: The Foundations of Cooperation in Economic Life edited by Herbert Gintis, Samuel Bowles, Robert Boyd & Ernst Fehr

doi:10.1038/440744b

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Back to the drawing board? p745

David Lindley reviews Knowing: The Nature of Physical Law by Michael Munowitz

doi:10.1038/440745a

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Science in culture: High impact p746

From protons to galaxies, Cosmic Collisions shows us what happens when things go bump.

Michael Hopkin

doi:10.1038/440746a

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News and Views

Palaeontology: A firm step from water to land p747

A project designed to discover fossils that illuminate the transition between fishes and land vertebrates has delivered the goods. At a stroke, our picture of that transition is greatly improved.

Per Erik Ahlberg and Jennifer A. Clack

doi:10.1038/440747a

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Evolution: It pays to laze p748

Lucy Odling-Smee

doi:10.1038/440748a

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Semiconductors: Spray-on silicon p749

Reports of the death of silicon electronics may well have been exaggerated. A technique that allows the deposition of silicon films from solution could harbinger the era of the inkjet-printed circuit.

Lisa Rosenberg

doi:10.1038/440749a

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Immunology: The pick of the nibbled bits p750

How does the immune system avoid potentially damaging responses against the body's own molecules? The answer lies partly in the ability of dendritic cells to sample their surroundings selectively.

Joel Swanson

doi:10.1038/440750a

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Solar system: When the dust unsettles p751

Two attempts to measure the isotopic composition of oxygen in the Sun from particles trapped in lunar soils give very different results. A rethink of why the Solar System is as it is might be required.

Gary R. Huss

doi:10.1038/440751a

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Archaeology: Failure and how to avoid it p752

Nothing lasts for ever, not least human civilizations. There are many reasons why societies stand or fall, and these lessons from the past require investigation at various places and on various timescales.

Kathleen D. Morrison

doi:10.1038/440752a

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Fluid dynamics: The rough with the smooth p754

Those who go with the flow assert that rough surfaces cause turbulence in fluids passing over them. The claim that, under certain conditions, the opposite is possible disturbs that cherished belief.

Kwing-So Choi

doi:10.1038/440754a

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Brief Communications

Palaeontology: Early Neolithic tradition of dentistry p755

Flint tips were surprisingly effective for drilling tooth enamel in a prehistoric population.

A. Coppa, L. Bondioli, A. Cucina, D. W. Frayer, C. Jarrige, J. -F. Jarrige, G. Quivron, M. Rossi, M. Vidale and R. Macchiarelli

doi:10.1038/440755a

First paragraph | Full Text | PDF (399K) | Supplementary information

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Parasitology: Parasite survives predation on its host p756

Fleur Ponton, Camille Lebarbenchon, Thierry Lefèvre, David G. Biron, David Duneau, David P. Hughes and Frédéric Thomas

doi:10.1038/440756a

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Brief Communications Arising

Animal behaviour: Chimpanzee choice and prosociality pE6

Richard J. Beninger and Vernon L. Quinsey

doi:10.1038/nature04758

First paragraph | Full Text | PDF (75K)

Animal behaviour: Chimpanzee choice and prosociality (Reply) pE6

Joan B. Silk, Sarah F. Brosnan, Jennifer Vonk, Joseph Henrich, Daniel J. Povinelli, Amanda S. Richardson, Susan P. Lambeth, Jenny Mascaro and Steven J. Shapiro

doi:10.1038/nature04759

First paragraph | Full Text | PDF (75K)

Articles

A Devonian tetrapod-like fish and the evolution of the tetrapod body plan p757

Edward B. Daeschler, Neil H. Shubin and Farish A. Jenkins, Jr

doi:10.1038/nature04639

Abstract | Full Text | PDF (523K) | Supplementary information

See also: Editor's summary | News and Views by Ahlberg & Clack

The pectoral fin of Tiktaalik roseae and the origin of the tetrapod limb p764

Neil H. Shubin, Edward B. Daeschler and Farish A. Jenkins, Jr

doi:10.1038/nature04637

Abstract | Full Text | PDF (899K) | Supplementary information

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Letters

A debris disk around an isolated young neutron star p772

Zhongxiang Wang, Deepto Chakrabarty and David L. Kaplan

doi:10.1038/nature04669

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Isotopic enhancements of ¹⁷O and ¹⁸O from solar wind particles in the lunar regolith p776

Trevor R. Ireland, Peter Holden, Marc D. Norman and Jodi Clarke

doi:10.1038/nature04611

First paragraph | Full Text | PDF (276K) | Supplementary information

See also: Editor's summary | News and Views by Huss

Quantum interference between two single photons emitted by independently trapped atoms p779

J. Beugnon, M. P. A. Jones, J. Dingjan, B. Darquié, G. Messin, A. Browaeys and P. Grangier

doi:10.1038/nature04628

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Solution-processed silicon films and transistors p783

Tatsuya Shimoda, Yasuo Matsuki, Masahiro Furusawa, Takashi Aoki, Ichio Yudasaka, Hideki Tanaka, Haruo Iwasawa, Daohai Wang, Masami Miyasaka and Yasumasa Takeuchi

doi:10.1038/nature04613

First paragraph | Full Text | PDF (330K)

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Increased Arctic cloud longwave emissivity associated with pollution from mid-latitudes p787

Timothy J. Garrett and Chuanfeng Zhao

doi:10.1038/nature04636

First paragraph | Full Text | PDF (192K)

Deciphering the evolution and metabolism of an anammox bacterium from a community genome p790

Marc Strous, Eric Pelletier, Sophie Mangenot, Thomas Rattei, Angelika Lehner, Michael W. Taylor, Matthias Horn, Holger Daims, Delphine Bartol-Mavel, Patrick Wincker, Valérie Barbe, Nuria Fonknechten, David Vallenet, Béatrice Segurens, Chantal Schenowitz-Truong, Claudine Médigue, Astrid Collingro, Berend Snel, Bas E. Dutilh, Huub J. M. Op den Camp, Chris van der Drift, Irina Cirpus, Katinka T. van de Pas-Schoonen, Harry R. Harhangi, Laura van Niftrik, Markus Schmid, Jan Keltjens, Jack van de Vossenberg, Boran Kartal, Harald Meier, Dmitrij Frishman, Martijn A. Huynen, Hans-Werner Mewes, Jean Weissenbach, Mike S. M. Jetten, Michael Wagner and Denis Le Paslier

doi:10.1038/nature04647

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Energetics reveals physiologically distinct castes in a eusocial mammal p795

M. Scantlebury, J. R. Speakman, M. K. Oosthuizen, T. J. Roper and N. C. Bennett

doi:10.1038/nature04578

First paragraph | Full Text | PDF (151K) | Supplementary information

See also: Editor's summary | News and Views by Odling-Smee

An unconventional myosin in Drosophila reverses the default handedness in visceral organs p798

Shunya Hozumi, Reo Maeda, Kiichiro Taniguchi, Maiko Kanai, Syuichi Shirakabe, Takeshi Sasamura, Pauline Spéder, Stéphane Noselli, Toshiro Aigaki, Ryutaro Murakami and Kenji Matsuno

doi:10.1038/nature04625

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Type ID unconventional myosin controls left–right asymmetry in Drosophila p803

Pauline Spéder, Géza Ádám and Stéphane Noselli

doi:10.1038/nature04623

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Toll-dependent selection of microbial antigens for presentation by dendritic cells p808

J. Magarian Blander and Ruslan Medzhitov

doi:10.1038/nature04596

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See also: News and Views by Swanson

Omega-3 and omega-6 fatty acids stimulate cell membrane expansion by acting on syntaxin 3 p813

Frédéric Darios and Bazbek Davletov

doi:10.1038/nature04598

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Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes p818

Nina Jones, Ivan M. Blasutig, Vera Eremina, Julie M. Ruston, Friedhelm Bladt, Hongping Li, Haiming Huang, Louise Larose, Shawn S.-C. Li, Tomoko Takano, Susan E. Quaggin and Tony Pawson

doi:10.1038/nature04662

First paragraph | Full Text | PDF (614K) | Supplementary information

Semi-conservative DNA replication through telomeres requires Taz1 p824

Kyle M. Miller, Ofer Rog and Julia Promisel Cooper

doi:10.1038/nature04638

First paragraph | Full Text | PDF (717K) | Supplementary information

Proton-coupled electron transfer drives the proton pump of cytochrome c oxidase p829

Ilya Belevich, Michael I. Verkhovsky and Mårten Wikström

doi:10.1038/nature04619

First paragraph | Full Text | PDF (302K) | Supplementary information

Crystal structure of the CorA Mg²⁺ transporter p833

Vladimir V. Lunin, Elena Dobrovetsky, Galina Khutoreskaya, Rongguang Zhang, Andrzej Joachimiak, Declan A. Doyle, Alexey Bochkarev, Michael E. Maguire, Aled M. Edwards and Christopher M. Koth

doi:10.1038/nature04642

First paragraph | Full Text | PDF (660K) | Supplementary information

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Naturejobs

The long road to equality p839

Lab visits show UK women physicists need better environment.

Paul Smaglik

doi:10.1038/nj7085-839a

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Breaking into business p840

Forget what your mother told you. Scientists looking for jobs in the business world need to learn to talk to strangers, says Monya Baker.

Monya Baker

doi:10.1038/nj7085-840a

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Fotis Kafatos, chairman, scientific council of the European Research Council p842

EMBL leader takes on the ERC.

Janet Wright

doi:10.1038/nj7085-842a

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A meeting of biomedical minds p842

Conference helps young scientist get plugged into international collaborations.

Tshaka Cunningham

doi:10.1038/nj7085-842b

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PhD survival guide p842

Graduate student seeks survival guides.

Andreas Andersson

doi:10.1038/nj7085-842c

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Highlight: The National Institutes of Health

doi:10.1038/nj0116

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Futures

My morning glory p844

What a way to start the day.

David Marusek

doi:10.1038/440844a

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