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Nature 440, 390-391 (23 March 2006) | doi:10.1038/440390b; Published online 22 March 2006

Trauma trials leave ethicists uneasy

Rex Dalton

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Issue of 'no consent' raises fundamental questions.

A US trial of an experimental blood substitute given to trauma patients who cannot give consent is stirring concern about the way that such 'no consent' trials are run.It is rare for experimental treatments to be given without consent.