Access
To read this story in full you will need to login or make a payment (see right).
Letter
Nature 440, 535-539 (23 March 2006) | doi:10.1038/nature04567; Received 23 September 2005; Accepted 22 December 2005
Open Innovation Challenges
-
Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
-
Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
nature jobs
Faculty Position in Neuroscience
- Montreal Neurological Institute
- Montreal, Quebec Canada
Oleo Chemistry
- Praj Matrix - Praj Industries Ltd
- Pune, Maharashtra Pune-411021 India
A P-type ATPase required for rice blast disease and induction of host resistance
Martin J. Gilbert1, Christopher R. Thornton1, Gavin E. Wakley1 & Nicholas J. Talbot1
- School of Biosciences, University of Exeter, Washington Singer Laboratories, Perry Road, Exeter EX4 4QG, UK
Correspondence to: Nicholas J. Talbot1 Correspondence and requests for materials should be addressed to N.J.T. (Email: n.j.talbot@exeter.ac.uk).
Abstract
To cause diseases in plants, pathogenic microorganisms have evolved mechanisms to deliver proteins directly into plant cells, where they suppress plant defences and facilitate tissue invasion1, 2, 3. How plant pathogenic fungi, which cause many of the world's most serious plant diseases, deliver proteins during plant infection is currently unknown. Here we report the characterization of a P-type ATPase-encoding gene, MgAPT2, in the economically important rice blast pathogen Magnaporthe grisea, which is required for exocytosis during plant infection. Targeted gene replacement showed that MgAPT2 is required for both foliar and root infection by the fungus, and for the rapid induction of host defence responses in an incompatible reaction.
Mgapt2 mutants are impaired in the secretion of a range of extracellular enzymes and accumulate abnormal Golgi-like cisternae. However, the loss of MgAPT2 does not significantly affect hyphal growth or sporulation, indicating that the establishment of rice blast disease involves the use of MgApt2-dependent exocytotic processes that operate during plant infection.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Biophysics Fungus punches its way inNature News and Views (23 Sep 1999)
Fungal gene clustersNature Biotechnology News and Views (01 Jan 2007)
See all 8 matches for News And ViewsRESEARCH
Trehalose synthesis and metabolism are required at different stages of plant infection by Magnaporthe griseaThe EMBO Journal Article (15 Jan 2003)
The genome sequence of the rice blast fungus Magnaporthe griseaNature Article (21 Apr 2005)
See all 35 matches for Research
