Folding DNA to create nanoscale shapes and patterns

doi:doi:10.1038/nature04586

From the following article:

Folding DNA to create nanoscale shapes and patterns

Paul W. K. Rothemund

Nature 440, 297-302 (16 March 2006)

doi:10.1038/nature04586

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Supplementary Notes 1–11

Notes on the design process; helix bending and the inter-helix gap; models and sequences; experimental methods; control experiments; patterning with dumbbell hairpins; the combination of shapes into larger structures; secondary structure of the scaffold and staples; the robustness of the scaffolded approach; the cost of the scaffold versus staples; and additiona references.

Supplementary Notes 1–11 - Download PDF file (9MB)

Supplementary Note 12

Full designs for all structures. Staple sequences are drawn out explicitly where they occur in the design. Because the designs are very large and the fonts are very small, this file will not print legibly. Instead of printing this file, open it in a PDF viewer and use the zoom feature to inspect the designs.

Supplementary Note 12 - Download PDF file (188KB)

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