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FIGURE 4. Proposed mechanism for the reaction catalysed by SyrB2.

From the following article:

Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis

Leah C. Blasiak, Frédéric H. Vaillancourt, Christopher T. Walsh and Catherine L. Drennan

Nature 440, 368-371 (16 March 2006)

doi:10.1038/nature04544

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See text for a description of the proposed steps. The crystallized form of SyrB2 is labelled A. The oxygen atom inserted into alphaKG is shown in red.

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