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Nature 440, E1-E2 (9 March 2006) | doi:10.1038/nature04685; Published online 8 March 2006

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Molecular genetics: DNA analysis of a putative dog clone

Heidi G. Parker1, Leonid Kruglyak2 & Elaine A. Ostrander1

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Arising from: B. C. Lee et al. Nature 436, 641 (2005); see also communication from the Seoul National University Investigation Committee, J. B. Lee and C. Park

In August 2005, Lee et al. reported the first cloning of a domestic dog from adult somatic cells1. This putative dog clone was the result of somatic-cell nuclear transfer from a fibroblast cell of a three-year-old male Afghan hound into a donor oocyte provided by a dog of mixed breed. In light of recent concerns regarding the creation of cloned human cell lines from the same institution2, 3, we have undertaken an independent test to determine the validity of the claims made by Lee et al.1.

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