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Nature 440, 158-159 (9 March 2006) | doi:10.1038/440158a; Published online 8 March 2006

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Neurobiology: How fast can you go?

Laura N. Borodinsky1

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Rhythmic activities such as walking need tight coordination. In mice, pace is tweaked by a specific set of spinal-cord neurons that, surprisingly, make the animals walk faster by inhibiting the underlying circuit.

Watch your step — walking may seem simple, but is actually quite a complex task. As with other rhythmic motor behaviours (breathing or swallowing, say), locomotion relies on a finely tuned neuronal network that is headquartered in the spinal cord1, 2.

  1. Laura N. Borodinsky is in the Neurobiology Section, Division of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0357, USA.
    Email: lborodin@biomail.ucsd.edu

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RESEARCH

V1 spinal neurons regulate the speed of vertebrate locomotor outputs

Nature Letters to Editor (09 Mar 2006)