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Figures and Tables

From the following article:

V1 spinal neurons regulate the speed of vertebrate locomotor outputs

Simon Gosgnach, Guillermo M. Lanuza, Simon J. B. Butt, Harald Saueressig, Ying Zhang, Tomoko Velasquez, Dieter Riethmacher, Edward M. Callaway, Ole Kiehn and Martyn Goulding

Nature 440, 215-219 (9 March 2006)

doi:10.1038/nature04545

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

V1 neurons are reduced in Pax6-/- and En1-DTA spinal cords.

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Figure 2

Mice lacking V1 neurons show slow locomotor-like activity.

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Figure 3

Motor neuron firing during locomotion in the Pax6-/- spinal cord is prolonged and shows rhythmic inhibition.

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Figure 4

En1tlZ/tlZ mice show a slowing of stepping movements.

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Figure 5

Acute silencing of V1 neurons via the allatostatin receptor causes a slowing of locomotor-like rhythmicity.

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