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Nature 439, 1004-1008 (28 December 2005) | doi:10.1038/nature04407;
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Postdoctoral Fellow - Computational Genomics - Team 78 – Ref: 80464
- Wellcome Trust Sanger Institute
- Hinxton, Cambridgeshire CB10 1, UK
Gastroenterologist
- South Atlanta Medical Clinic, PC (GI Group)
- Atlanta, GA, USA
A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malaria
Mono-allelic expression of gene families is used by many organisms to mediate phenotypic variation of surface proteins. In the apicomplexan parasite Plasmodium falciparum, responsible for the severe form of malaria in humans, this is exemplified by antigenic variation of the highly polymorphic P.
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