Table of contents


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Authors

Making the paper: Christl Donnelly pxi

Badger behaviour complicates attempts to control TB in cattle.

doi:10.1038/7078xia


Abstractions pxi

doi:10.1038/7078xib


Quantified: Portugal pxi

doi:10.1038/7078xic


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Editorials

Think global p763

'Virtual globe' software is transforming our ability to visualize and hypothesize in three dimensions. Educators take note.

doi:10.1038/439763a


It's academic p763

The development of scientific academies could help to put science to work in Africa.

doi:10.1038/439763a


NASA in reverse p764

The US space agency's relationship with scientists is hitting a new low.

doi:10.1038/439764a


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Research Highlights

Research highlights p766

doi:10.1038/439766a


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News

US space scientists rage over axed projects p768

Critics say proposed cuts will devastate the field.

Tony Reichhardt

doi:10.1038/439768a


Disgraced cloner's ally is cleared of misconduct p768

But Hwang's US collaborator is chided for 'research misbehaviour'.

Emma Marrisand Erika Check

doi:10.1038/439768b


Biomedicine to sell itself as a local hero p769

Lobbyists plan to push the economic benefits of medical research.

Erika Check

doi:10.1038/439769a


Prestige is factored into journal ratings p770

'Y-factor' measures quality as well as quantity of citations.

Philip Ball

doi:10.1038/439770a


Plans to pare down climate centre anger UK ecologists p770

British response to global warming will be impaired, say critics.

Jim Giles

doi:10.1038/439770b


Doubts hang over source of bird flu spread p772

How did H5N1 spread to Africa and the European Union?

Declan Butler

doi:10.1038/439772a


Thai dogs carry bird-flu virus, but will they spread it? p773

Antibodies to H5N1 found in village dogs and cats.

Declan Butler

doi:10.1038/439773a


Sidelines p773

doi:10.1038/439773b


Calls to conserve biodiversity hotspots p774

Indonesia's 'lost world' could be under threat from poachers.

David Cyranoski

doi:10.1038/439774a


News in brief p775

doi:10.1038/439775a


Correction p775

doi:10.1038/439775b


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News Features

Virtual globes: The web-wide world p776

Life happens in three dimensions, so why doesn't science? Declan Butler discovers that online tools, led by the Google Earth virtual globe, are changing the way we interact with spatial data.

Declan Butler

doi:10.1038/439776a


Medical research: Them and us no longer p779

Scientists and medical doctors view research through different lenses — but the gulf in outlook between the two tribes isn't what it used to be. Meredith Wadman reports.

Meredith Wadman

doi:10.1038/439779a


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Business

Across China's frontier p781

China has become the preferred place for international firms to open research labs — and Japan is leading the way, reports Ichiko Fuyuno.

doi:10.1038/439781a


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Correspondence

Why negatives should be viewed as positives p782

Bob O'Hara, Mike S. Fowlerand Christine A. Johnson

doi:10.1038/439782a


A simple system of checks and balances to cut fraud p782

Xiangzhong Yang, K. Eggan, G. Seidel, Jr, R. Jaenischand D. Melton

doi:10.1038/439782b


Peer review could be improved by market forces p782

Klaus Jaffe

doi:10.1038/439782c


Bureaucracy won't change the character of a cheat p782

Phil Bentley

doi:10.1038/439782d


Pressure also leads to worthless publications p784

Lindomar B. de Carvalho

doi:10.1038/439784a


It's difficult to publish contradictory findings p784

Thomas E. DeCoursey

doi:10.1038/439784b


Data audit would reduce unethical behaviour p784

Adil E. Shamoo

doi:10.1038/439784c


Discourse among referees and editors would help p784

Debomoy K. Lahiri

doi:10.1038/439784d


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Commentary

Mapping disaster zones p787

Google Earth software proved effective during relief efforts in New Orleans and Pakistan, say Illah Nourbakhsh and colleagues. Is there more to be gained than lost from opening up disaster operations to the wider public?

Illah Nourbakhsh, Randy Sargent, Anne Wright, Kathryn Cramer, Brian McClendonand Michael Jones

doi:10.1038/439787a


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Books and Arts

Enough is enough p789

Economic growth should be viewed as a means to an end, not an end in itself.

doi:10.1038/439789a


Super science p790

doi:10.1038/439790a


Incomplete mathematics p790

doi:10.1038/439790b


Exhibition: Classifying the past p791

Alexis Clements

doi:10.1038/439791a


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News and Views

全球的気候変動:水サイクルに関する新知見

Global change: The water cycle freshens up p793

Rivers are delivering increasing amounts of fresh water to the ocean. The cause seems to be the influence that higher concentrations of atmospheric carbon dioxide are having on water use by plants.

Damon Matthews

doi:10.1038/439793a


発生生物学:沈黙に通じる2つの道はつながっている

Developmental biology: Two paths to silence merge p794

To maintain their identity across generations, specialized cells must heritably repress swathes of genes — keeping active only genes necessary for the cell's purpose. Now it seems two repressive pathways join forces.

Panthea Taghaviand Maarten van Lohuizen

doi:10.1038/439794a


化学:イオン性液体の揮発

Chemistry: Volatile times for ionic liquids p797

Ionic liquids are useful substances, but in certain applications their utility is limited because they are involatile — or so we thought. In fact, some ionic liquids can be distilled, and even thermally separated.

Peter Wasserscheid

doi:10.1038/439797a


遺伝学:コピー数はいくつ?

Genetics: Copies count p798

Some genes have more than one copy, and the copy number can differ among individuals. But does this variation affect the person involved? It seems susceptibility to certain common diseases can be altered.

Joseph H. Nadeauand Charles Lee

doi:10.1038/439798a


分光学:地球磁場を使うNMR

Spectroscopy: NMR down to Earth p799

High-precision nuclear magnetic resonance spectroscopy generally requires the use of powerful magnets. But using Earth's magnetic field allows us to gain some of the same information on the cheap.

Janez Stepis caronnik

doi:10.1038/439799a


50 & 100 years ago p799

doi:10.1038/439799b


地図作成学:人口を表す俯瞰地図

Cartography: A popular perspective p800

Richard Webb

doi:10.1038/439800a


化学:結合の短さ

Chemistry: Brevity for bonds p801

Fashion design? Game-playing? Designing the shortest bond between two carbon atoms can seem to have elements of such apparently ephemeral pursuits. But it can also stretch the chemist's creativity.

Jay S. Siegel

doi:10.1038/439802a


微生物学:防護用ラケット

Microbiology: Protection racket p802

Helen Dell

doi:10.1038/439802a


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Brief Communications

Invasion and the evolution of speed in toads p803

Cane toads seem to have honed their dispersal ability to devastating effect over the generations.

Benjamin L. Phillips, Gregory P. Brown, Jonathan K. Webband Richard Shine

doi:10.1038/439803a


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Articles

植物:自家不和合性タバコが行っているS-RNアーゼの区画化およびHT-Bの分解

Compartmentalization of S-RNase and HT-B degradation in self-incompatible Nicotiana p805

Ariel Goldraij, Katsuhiko Kondo, Christopher B. Lee, C. Nathan Hancock, Mayandi Sivaguru, Sonia Vazquez-Santana, Sunran Kim, Thomas E. Phillips, Felipe Cruz-Garciaand Bruce McClure

doi:10.1038/nature04491


細胞:JmjCドメインをもつタンパク質ファミリーによるヒストンの脱メチル化

Histone demethylation by a family of JmjC domain-containing proteins p811

Yu-ichi Tsukada, Jia Fang, Hediye Erdjument-Bromage, Maria E. Warren, Christoph H. Borchers, Paul Tempstand Yi Zhang

doi:10.1038/nature04433


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Letters

宇宙:回転する中性子星からのトランジェントな電波バースト

Transient radio bursts from rotating neutron stars p817

M. A. McLaughlin, A. G. Lyne, D. R. Lorimer, M. Kramer, A. J. Faulkner, R. N. Manchester, J. M. Cordes, F. Camilo, A. Possenti, I. H. Stairs, G. Hobbs, N. D'Amico, M. Burgayand J. T. O'Brien

doi:10.1038/nature04440


宇宙:鉄隕石は地球型惑星領域で形成された微惑星の残骸と考えられる

Iron meteorites as remnants of planetesimals formed in the terrestrial planet region p821

William F. Bottke, David Nesvorný, Robert E. Grimm, Alessandro Morbidelliand David P. O'Brien

doi:10.1038/nature04536


物理:半金属強磁性体CrO2を通るスピン三重項超伝導電流

A spin triplet supercurrent through the half-metallic ferromagnet CrO2 p825

R. S. Keizer, S. T. B. Goennenwein, T. M. Klapwijk, G. Miao, G. Xiaoand A. Gupta

doi:10.1038/nature04499


物理:静的な粉粒体に働く力のネットワークのスケール不変性と普遍性

Scale invariance and universality of force networks in static granular matter p828

Srdjan Ostojic, Ellák Somfaiand Bernard Nienhuis

doi:10.1038/nature04549


化学:イオン性液体の蒸留と揮発性

The distillation and volatility of ionic liquids p831

Martyn J. Earle, José M.S.S. Esperança, Manuela A. Gilea, José N. Canongia Lopes, Luís P.N. Rebelo, Joseph W. Magee, Kenneth R. Seddonand Jason A. Widegren

doi:10.1038/nature04451


気候:大陸の河川流出量の記録における二酸化炭素の直接的な影響の検出

Detection of a direct carbon dioxide effect in continental river runoff records p835

N. Gedney, P. M. Cox, R. A. Betts, O. Boucher, C. Huntingfordand P. A. Stott

doi:10.1038/nature04504


進化:オーストラリアの漸新世-中新世の地層で見つかったMacrostomata類に入らない大型ヘビ類Yurlunggurの頭骨

Skull of the large non-macrostomatan snake Yurlunggur from the Australian Oligo-Miocene p839

John D. Scanlon

doi:10.1038/nature04137


獣疫学:広範囲に及ぶアナグマ駆除がウシの結核に及ぼすプラスとマイナスの影響

Positive and negative effects of widespread badger culling on tuberculosis in cattle p843

Christl A. Donnelly, Rosie Woodroffe, D. R. Cox, F. John Bourne, C. L. Cheeseman, Richard S. Clifton-Hadley, Gao Wei, George Gettinby, Peter Gilks, Helen Jenkins, W. Thomas Johnston, Andrea M. Le Fevre, John P. McInerneyand W. Ivan Morrison

doi:10.1038/nature04454


植物:海洋性の浮遊細菌と古細菌の間でのプロテオロドプシン遺伝子の水平伝播

Proteorhodopsin lateral gene transfer between marine planktonic Bacteria and Archaea p847

Niels-Ulrik Frigaard, Asuncion Martinez, Tracy J. Mincerand Edward F. DeLong

doi:10.1038/nature04435


遺伝:Fcgr3のコピー数多型がラットおよびヒトにおいて糸球体腎炎の素因となる

Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans p851

Timothy J. Aitman, Rong Dong, Timothy J. Vyse, Penny J. Norsworthy, Michelle D. Johnson, Jennifer Smith, Jonathan Mangion, Cheri Roberton-Lowe, Amy J. Marshall, Enrico Petretto, Matthew D. Hodges, Gurjeet Bhangal, Sheetal G. Patel, Kelly Sheehan-Rooney, Mark Duda, Paul R. Cook, David J. Evans, Jan Domin, Jonathan Flint, Joseph J. Boyle, Charles D. Puseyand H. Terence Cook

doi:10.1038/nature04489


遺伝:遺伝子調節へのボトムアップ・アプローチ

A bottom-up approach to gene regulation p856

Nicholas J. Guido, Xiao Wang, David Adalsteinsson, David McMillen, Jeff Hasty, Charles R. Cantor, Timothy C. Elstonand J. J. Collins

doi:10.1038/nature04473


遺伝:真核生物遺伝子の発現にみられる外因性変動の起源

Origins of extrinsic variability in eukaryotic gene expression p861

Dmitri Volfson, Jennifer Marciniak, William J. Blake, Natalie Ostroff, Lev S. Tsimringand Jeff Hasty

doi:10.1038/nature04281


脳:霊長類の扁桃体は学習中の視覚刺激の正負の価値を表わす

The primate amygdala represents the positive and negative value of visual stimuli during learning p865

Joseph J. Paton, Marina A. Belova, Sara E. Morrisonand C. Daniel Salzman

doi:10.1038/nature04490


細胞:ポリコーム群タンパク質EZH2はDNAメチル化を直接制御する

The Polycomb group protein EZH2 directly controls DNA methylation p871

Emmanuelle Viré, Carmen Brenner, Rachel Deplus, Loïc Blanchon, Mario Fraga, Céline Didelot, Lluis Morey, Aleyde Van Eynde, David Bernard, Jean-Marie Vanderwinden, Mathieu Bollen, Manel Esteller, Luciano Di Croce, Yvan de Launoitand François Fuks

doi:10.1038/nature04431


細胞:マイナス端方向へ移動するキネシンNcdはレバー-アームの回転によって移動する

A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd p875

Nicholas F. Endres, Craig Yoshioka, Ronald A. Milliganand Ronald D. Vale

doi:10.1038/nature04320


生化学:酸化DNA/RNA修復酵素AlkBの触媒複合体の結晶構造

Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB p879

Bomina Yu, William C. Edstrom, Jordi Benach, Yoshitomo Hamuro, Patricia C. Weber, Brian R. Gibneyand John F. Hunt

doi:10.1038/nature04561


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Naturejobs

Prospect

Valuable lessons p885

Help in developing the 'soft' skills.

Paul Smaglik

doi:10.1038/nj7078-885a


Special Report

Drug hunt p886

In the first of a series of articles on the drug pipeline, Hannah Hoag looks at the opportunities in selecting leads.

Hannah Hoag

doi:10.1038/nj7078-886a


Career Views

Giulio Superti-Furga, scientific director and chief executive, Research Center for Molecular Medicine, Austrian Academy of Sciences p888

Proteomics expert returns to academia after a stint in biotech.

Corie Lok

doi:10.1038/nj7078-888a


The changing face of Japan p888

Government invests in careers of young Japanese researchers.

Ichiko Fuyuno

doi:10.1038/nj7078-888b


The end of the affair p888

Final-year graduate student looks beyond the bench for future career.

Katja Bargum

doi:10.1038/nj7078-888c


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Futures

Daddy's slight miscalculation p890

Science at the cutting edge.

Ashley Pellegrino

doi:10.1038/439890a


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