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Developmental biology

Two paths to silence merge

To maintain their identity across generations, specialized cells must heritably repress swathes of genes — keeping active only genes necessary for the cell's purpose. Now it seems two repressive pathways join forces.

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Figure 1: Making epigenetic methylation marks.
Figure 2: Inheritance of epigenetic memory.

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Taghavi, P., van Lohuizen, M. Two paths to silence merge. Nature 439, 794–795 (2006). https://doi.org/10.1038/439794a

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