Table of contents
Volume 439 Number 7077 pp633-762
Editorials
Physics fights back p633
The physical sciences are strongly favoured in President Bush's 2007 budget request — but researchers can't count their chickens yet.
doi:10.1038/439633a
Network of concern p633
Only biologists can effectively police the misuse of biological agents.
doi:10.1038/439633b
Japan's research conduct p634
A framework is required for investigations into scientific misconduct in Japan.
doi:10.1038/439634a
News
Dealer unearths Hooke's Royal Society notes p638
Original manuscript could settle old scores.
Jim Giles
doi:10.1038/439638a
Drop in HIV infection rate used to justify focus on morality p638
Abstinence campaigners claim success over AIDS.
Erika Check
doi:10.1038/439638b
Possible planets left with no name p639
Astronomers remain divided over definition.
Mark Peplow
doi:10.1038/439639a
Sidelines p640
doi:10.1038/439640a
One place, one parent, two species p640
Island hosts double boost for evolutionary theory.
Michael Hopkin
doi:10.1038/439640b
Political strife set to delay EU funds p640
European Research Council faces problematic beginning.
Quirin Schiermeier
doi:10.1038/439640c
Space rocks wanted: cash paid p642
University bids to save meteorites for science.
Rex Dalton
doi:10.1038/439642a
Journal lays bare remarks from peer reviewers p642
Cloak of anonymity shed by new publication.
Emma Marris
doi:10.1038/439642b
Special Report
Physics wins the US budget race p644
Energy and competitiveness are the buzzwords in George W. Bush's proposal for spending in the next fiscal year. But will the president's push really benefit researchers?
Geoff Brumfiel and Emma Marris
doi:10.1038/439644a
The scientific balance of power p646
doi:10.1038/439646a
News Features
Fractals and art: In the hands of a master p648
Fractal analysis has been used to assess the authenticity of paintings purporting to be the work of Jackson Pollock. Alison Abbott reports.
doi:10.1038/439648a
Cloning: Mining the secrets of the egg p652
doi:10.1038/439652a
First paragraph | Full Text | PDF (1,185K)
Cloning: Do we even need eggs? p655
doi:10.1038/439655a
First paragraph | Full Text | PDF (602K)
Business
No end in sight for stem-cell odyssey p658
Advanced Cell Technology plans to tread cautiously on the ground left vacant by the collapse of a South Korean scientist's claims to have cloned a human embryo, as David Cyranoski reports.
doi:10.1038/439658a
In brief p659
doi:10.1038/439659a
Market watch p659
doi:10.1038/439659b
Correspondence
Climate may not be linked with circulation slowdown p660
Eric Steig
doi:10.1038/439660a
No unfairness in funding of Croatian minister's project p660
Stjepan Risovi
doi:10.1038/439660b
Dwindling fish numbers already of concern in 1883 p660
David W. Sims and Alan J. Southward
doi:10.1038/439660c
Problems at plutonium lab need more than a quick fix p660
Martha Priebat
doi:10.1038/439660d
Books and Arts
A healthy dose of genetics p661
How much has genetics contributed to advances in medicine?
Uta Francke reviews Moments of Truth in Genetic Medicine by Susan Lindee
doi:10.1038/439661a
In the minds of animals p662
Scott Creel reviews Animal Passions and Beastly Virtues: Reflections on Redecorating Nature by Marc Bekoff
doi:10.1038/439662a
A ship, gradually lowering sail p663
Douwe Draaisma reviews The Long History of Old Age edited by Pat Thane
doi:10.1038/439663a
Science in culture: Nuclear-powered image p664
A short film playing with concepts of quantum physics makes it big.
Alison Abbott
doi:10.1038/439664a
News and Views
Palaeontology: A Jurassic tyrant is crowned p665
A newly discovered species of dinosaur, characterized by a wonderfully elaborate head crest, is the oldest known member of the lineage that culminated in Tyrannosaurus rex more than 90 million years later.
Thomas R. Holtz Jr
doi:10.1038/439665a
See also: Editor's summary
Chemical biology: Aptamers in nanoland p666
Chameleon-like nanoparticles of gold can be used to indicate the presence of various biomolecules. Adding aptamers — DNA strands that bind only to specific molecules — to the mix opens up further possibilities.
Michael Famulok and Günter Mayer
doi:10.1038/439666a
50 & 100 years ago p667
doi:10.1038/439667a
Immunology: Exhausted T cells perk up p669
During persistent infections, the immune cells responsible for killing infected cells and maintaining inflammation gradually stop functioning, allowing the pathogen to thrive. But can this process be reversed?
Matthew A. Williams and Michael J. Bevan
doi:10.1038/439669a
See also: Editor's summary | Authors
Earth science: The rise and growth of Tibet p670
It is not difficult to be impressed by the grandeur of high mountainous regions, but it is difficult to reconstruct how the elevation of such regions evolved. A study of the Tibetan plateau does just that.
Andreas Mulch and C. Page Chamberlain
doi:10.1038/439670a
See also: Editor's summary
Semiconductor physics: Transport news p671
Conventionally, conduction in silicon is enhanced by doping — adding impurities that change the material's electronic structure. But exploiting surface effects in thin silicon films may offer yet other opportunities.
John J. Boland
doi:10.1038/439671a
Evolution: Memories of mammoths p673
Henry Gee
doi:10.1038/439673a
See also: Editor's summary
Brief Communications
Volcanoes and climate: Krakatoa's signature persists in the ocean p675
This huge eruption slowed sea-level rise and ocean warming well into the following century.
P. J. Gleckler, T. M. L. Wigley, B. D. Santer, J. M. Gregory, K. AchutaRao and K. E. Taylor
doi:10.1038/439675a
First paragraph | Full Text | PDF (238K) | Supplementary information
See also: Editor's summary
Articles
Palaeo-altimetry of the late Eocene to Miocene Lunpola basin, central Tibet p677
David B. Rowley and Brian S. Currie
doi:10.1038/nature04506
Abstract | Full Text | PDF (323K)
See also: Editor's summary | News and Views by Mulch & Chamberlain
Restoring function in exhausted CD8 T cells during chronic viral infection p682
Daniel L. Barber, E. John Wherry, David Masopust, Baogong Zhu, James P. Allison, Arlene H. Sharpe, Gordon J. Freeman and Rafi Ahmed
doi:10.1038/nature04444
Abstract | Full Text | PDF (1,663K) | Supplementary information
See also: Editor's summary | News and Views by Williams & Bevan | Authors
Structural mechanism of plant aquaporin gating p688
Susanna Törnroth-Horsefield, Yi Wang, Kristina Hedfalk, Urban Johanson, Maria Karlsson, Emad Tajkhorshid, Richard Neutze and Per Kjellbom
doi:10.1038/nature04316
Abstract | Full Text | PDF (462K) | Supplementary information
See also: Editor's summary
Letters
Discovery of very-high-energy 
-rays from the Galactic Centre ridge p695
F. Aharonian, A. G. Akhperjanian, A. R. Bazer-Bachi, M. Beilicke, W. Benbow, D. Berge, K. Bernlöhr, C. Boisson, O. Bolz, V. Borrel, I. Braun, F. Breitling, A. M. Brown, P. M. Chadwick, L.-M. Chounet, R. Cornils, L. Costamante, B. Degrange, H. J. Dickinson, A. Djannati-Ataï, L. O'C. Drury, G. Dubus, D. Emmanoulopoulos, P. Espigat, F. Feinstein, G. Fontaine, Y. Fuchs, S. Funk, Y. A. Gallant, B. Giebels, S. Gillessen, J. F. Glicenstein, P. Goret, C. Hadjichristidis, D. Hauser, M. Hauser, G. Heinzelmann, G. Henri, G. Hermann, J. A. Hinton, W. Hofmann, M. Holleran, D. Horns, A. Jacholkowska, O. C. de Jager, B. Khélifi, S. Klages, Nu. Komin, A. Konopelko, I. J. Latham, R. Le Gallou, A. Lemière, M. Lemoine-Goumard, N. Leroy, T. Lohse, A. Marcowith, J. M. Martin, O. Martineau-Huynh, C. Masterson, T. J. L. McComb, M. de Naurois, S. J. Nolan, A. Noutsos, K. J. Orford, J. L. Osborne, M. Ouchrif, M. Panter, G. Pelletier, S. Pita, G. Pühlhofer, M. Punch, B. C. Raubenheimer, M. Raue, J. Raux, S. M. Rayner, A. Reimer, O. Reimer, J. Ripken, L. Rob, L. Rolland, G. Rowell, V. Sahakian, L. Saugé, S. Schlenker, R. Schlickeiser, C. Schuster, U. Schwanke, M. Siewert, H. Sol, D. Spangler, R. Steenkamp, C. Stegmann, J.-P. Tavernet, R. Terrier, C. G. Théoret, M. Tluczykont, C. van Eldik, G. Vasileiadis, C. Venter, P. Vincent, H. J. Völk and S. J. Wagner
doi:10.1038/nature04467
First paragraph | Full Text | PDF (380K) | Supplementary information
See also: Editor's summary | Authors
Anti-planetward auroral electron beams at Saturn p699
J. Saur, B. H. Mauk, D. G. Mitchell, N. Krupp, K. K. Khurana, S. Livi, S. M. Krimigis, P. T. Newell, D. J. Williams, P. C. Brandt, A. Lagg, E. Roussos and M. K. Dougherty
doi:10.1038/nature04401
First paragraph | Full Text | PDF (335K)
See also: Editor's summary
Electronic transport in nanometre-scale silicon-on-insulator membranes p703
Pengpeng Zhang, Emma Tevaarwerk, Byoung-Nam Park, Donald E. Savage, George K. Celler, Irena Knezevic, Paul G. Evans, Mark A. Eriksson and Max G. Lagally
doi:10.1038/nature04501
First paragraph | Full Text | PDF (278K)
See also: News and Views by Boland
Initial corrosion observed on the atomic scale p707
F. U. Renner, A. Stierle, H. Dosch, D. M. Kolb, T.-L. Lee and J. Zegenhagen
doi:10.1038/nature04465
First paragraph | Full Text | PDF (542K)
See also: Editor's summary
Winter forest soil respiration controlled by climate and microbial community composition p711
Russell K. Monson, David L. Lipson, Sean P. Burns, Andrew A. Turnipseed, Anthony C. Delany, Mark W. Williams and Steven K. Schmidt
doi:10.1038/nature04555
First paragraph | Full Text | PDF (287K)
See also: Editor's summary
A basal tyrannosauroid dinosaur from the Late Jurassic of China p715
Xing Xu, James M. Clark, Catherine A. Forster, Mark A. Norell, Gregory M. Erickson, David A. Eberth, Chengkai Jia and Qi Zhao
doi:10.1038/nature04511
First paragraph | Full Text | PDF (321K) | Supplementary information
See also: Editor's summary | News and Views by Holtz Jr
Sympatric speciation in Nicaraguan crater lake cichlid fish p719
Marta Barluenga, Kai N. Stölting, Walter Salzburger, Moritz Muschick and Axel Meyer
doi:10.1038/nature04325
First paragraph | Full Text | PDF (826K) | Supplementary information
See also: Editor's summary
Multiplex amplification of the mammoth mitochondrial genome and the evolution of Elephantidae p724
Johannes Krause, Paul H. Dear, Joshua L. Pollack, Montgomery Slatkin, Helen Spriggs, Ian Barnes, Adrian M. Lister, Ingo Ebersberger, Svante Pääbo and Michael Hofreiter
doi:10.1038/nature04432
First paragraph | Full Text | PDF (300K) | Supplementary information
See also: Editor's summary | News and Views by Gee
Localized maternal orthodenticle patterns anterior and posterior in the long germ wasp Nasonia p728
Jeremy A. Lynch, Ava E. Brent, David S. Leaf, Mary Anne Pultz and Claude Desplan
doi:10.1038/nature04445
First paragraph | Full Text | PDF (310K) | Supplementary information
See also: Editor's summary
Gamma-band synchronization in visual cortex predicts speed of change detection p733
Thilo Womelsdorf, Pascal Fries, Partha P. Mitra and Robert Desimone
doi:10.1038/nature04258
First paragraph | Full Text | PDF (342K) | Supplementary information
Whole-cell patch-clamp measurements of spermatozoa reveal an alkaline-activated Ca2+ channel p737
Yuriy Kirichok, Betsy Navarro and David E. Clapham
doi:10.1038/nature04417
First paragraph | Full Text | PDF (1,384K) | Supplementary information
See also: Editor's summary
Structural basis for Duffy recognition by the malaria parasite Duffy-binding-like domain p741
Saurabh Kumar Singh, Rachna Hora, Hassan Belrhali, Chetan E. Chitnis and Amit Sharma
doi:10.1038/nature04443
First paragraph | Full Text | PDF (437K) | Supplementary information
See also: Authors
Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection p745
Koert J. Stittelaar, Johan Neyts, Lieve Naesens, Geert van Amerongen, Rob F. van Lavieren, Antonin Holý, Erik De Clercq, Hubert G. M. Niesters, Edwin Fries, Chantal Maas, Paul G. H. Mulder, Ben A. M. van der Zeijst and Albert D. M. E. Osterhaus
doi:10.1038/nature04295
First paragraph | Full Text | PDF (419K) | Supplementary information
See also: Editor's summary
Molecular characterization of Ph1 as a major chromosome pairing locus in polyploid wheat p749
Simon Griffiths, Rebecca Sharp, Tracie N. Foote, Isabelle Bertin, Michael Wanous, Steve Reader, Isabelle Colas and Graham Moore
doi:10.1038/nature04434
First paragraph | Full Text | PDF (307K) | Supplementary information
ClpS is an essential component of the N-end rule pathway in Escherichia coli p753
A. Erbse, R. Schmidt, T. Bornemann, J. Schneider-Mergener, A. Mogk, R. Zahn, D. A. Dougan and B. Bukau
doi:10.1038/nature04412
First paragraph | Full Text | PDF (459K) | Supplementary information
Naturejobs
ProspectVariations on a theme p757
Presenting Naturejobs' graduate journalists — class of 2006.
Paul Smaglik
doi:10.1038/nj7077-757a
Postdocs and Students
When personalities clash p758
Conflict in the laboratory can depress attitudes, dampen prospects or even derail young science careers. Kendall Powell finds out how to resolve issues and stay on track.
Kendall Powell
doi:10.1038/nj7077-758a
Career Views
Hendrik Weerts, director, high-energy physics division, Argonne National Laboratory, Argonne, Illinois p760
Particle physicist takes on administrative role to help guide the field.
Virginia Gewin
doi:10.1038/nj7077-760a
Dabbling in science journalism p760
Graduate course teaches students and postdocs the importance of public communication.
Lina Nordquist
doi:10.1038/nj7077-760b
PhD TV p760
Why graduate students won't make it on TV.
Milan de Vries
doi:10.1038/nj7077-760c
