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Authors

Making the paper pix

Plotting a course through the ethical minefield of stem cells.

Rudolph Jaenisch

doi:10.1038/7073ixa


Abstractions pix

doi:10.1038/7073ixb


Quantified: Costa Rica pix

doi:10.1038/7073ixc


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Editorials

Ethics and fraud p117

The trajectory of the Hwang scandal highlights the shortness of the path between unethical behaviour and outright misconduct.

doi:10.1038/439117a


Three cheers for peers p118

Thanks are due to researchers who act as referees, as editors resolve their often contradictory advice.

doi:10.1038/439118a


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Research Highlights

Research highlights p120

doi:10.1038/439120a


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News

Verdict: Hwang's human stem cells were all fakes p122

Korean scientist did not clone a human embryo but did clone a dog.

David Cyranoski

doi:10.1038/439122a


French research chief quits over reforms p122

Plans for restructured agency prompt resignation.

Declan Butler

doi:10.1038/439122b


Yes, but will it jump? p124

Experts divided on whether H5N1 bird flu will gain ability to spread between people.

Declan Butler

doi:10.1038/439124a


Sidelines p126

doi:10.1038/439126a


DNA tests put death penalty under fire p126

Campaigners hope re-examination of evidence will undermine capital punishment.

Emma Marris

doi:10.1038/439126b


Bird lovers keep sharp eye on owls p127

Visitors from Europe ruffle conservationists' feathers.

Jim Giles

doi:10.1038/439127a


Methane finding baffles scientists p128

Plant production of greenhouse gas throws up questions for climate models.

Quirin Schiermeier

doi:10.1038/439128a


News in brief p129

doi:10.1038/439129a


Correction p129

doi:10.1038/439129b


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News Features

Origins of DNA: Base invaders p130

Could viruses have invented DNA as a way to sneak into cells? John Whitfield investigates.

doi:10.1038/439130a

See also: Editor's summary


Space exploration: A shot in the dark? p132

Japan's mission to collect a sample from a distant asteroid looks to have ended in failure. Ichiko Fuyuno investigates how the setback will affect Japan's struggling space programme.

doi:10.1038/439132a

See also: Editor's summary


Prion disease: The shape of things to come p134

A number of fatal brain diseases are linked to misfolded proteins, an effect researchers are mimicking in the lab. But as they generate new versions of these malformed molecules, could they be creating a monster? Roxanne Khamsi finds out.

doi:10.1038/439134a


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Business

All systems go p136

Industrial chemists are borrowing techniques from drug researchers to track down materials with desirable properties. Andrea Chipman reports.

doi:10.1038/439136a


In brief p137

doi:10.1038/439137a


Market Watch p137

doi:10.1038/439137b


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Correspondence

Neuroscience gears up for duel on the issue of brain versus deity p138

Kenneth S. Kosik

doi:10.1038/439138a


Testing is necessary on animals as well as in vitro p138

Andrew Huxley

doi:10.1038/439138b


Animal-rights extremists lose public support p138

P. Browne

doi:10.1038/439138c


Why should child care be seen as a women's issue? p138

Maria José Hötzel

doi:10.1038/439138d


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Books and Arts

In the grey zone p139

If behaviour arises from interactions between genes and the environment, in what sense is it hardwired?

Erik Parens reviews Hardwired Behavior: What Neuroscience Reveals about Morality by Laurence R. Tancredi

doi:10.1038/439139a

See also: Editor's summary


The monster that is medicine p140

W. F. Bynum reviews Dr Golem: How to Think about Medicine by Harry Collins and Trevor Pinch

doi:10.1038/439140a


A little judgement p141

Harry Collins reviews Nano-Hype: The Truth Behind the Nanotechnology Buzz by David M. Berube

doi:10.1038/439141a


Science in culture: A bigger picture of apes p142

The recent King Kong film highlights how our perceptions of gorillas have changed.

Janet Browne

doi:10.1038/439142a


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News and Views

Extinctions: A message from the frogs p143

The harlequin frogs of tropical America are at the sharp end of climate change. About two-thirds of their species have died out, and altered patterns of infection because of changes in temperature seem to be the cause.

Andrew R. Blaustein and Andy Dobson

doi:10.1038/439143a

See also: Editor's summary


Space Physics: Breaking through the lines p144

Magnetic field lines are known to reorganize themselves in plasmas, converting magnetic to particle energy. Evidence harvested from the solar wind implies that the scale of the effect is larger than was thought.

Götz Paschmann

doi:10.1038/439144a

See also: Editor's summary


Medicine: Politic stem cells p145

Research on embryonic stem cells holds huge promise for understanding and treating disease. Many people oppose such research on religious and ethical grounds, but two new methods may bypass some of these objections.

Irving L. Weissman

doi:10.1038/439145a

See also: Editor's summary


50 & 100 years ago p147

doi:10.1038/439147a


Global change: A green source of surprise p148

Living terrestrial vegetation emits large amounts of methane into the atmosphere. This unexpected finding, if confirmed, will have an impact on both greenhouse-gas accounting and research into sources of methane.

David C. Lowe

doi:10.1038/439148a

See also: Editor's summary


Behaviour: Smells, brains and hormones p149

Contrary to the traditional view, the main olfactory pathway can mediate responses to pheromones as well as to common odours. Recent studies show that pheromone-activated hormonal systems extend widely within the brain.

Gordon M. Shepherd

doi:10.1038/439149a


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Obituary

Lawrence C. Katz (1956–2005) p152

Neuroscientist who helped to make sense of sense.

Carla J. Shatz

doi:10.1038/439152a


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Brief Communications

Teaching in tandem-running ants p153

Tapping into the dialogue between leader and follower reveals an unexpected social skill.

Nigel R. Franks and Tom Richardson

doi:10.1038/439153a

See also: Editor's summary


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Articles

Hit-and-run planetary collisions p155

Erik Asphaug, Craig B. Agnor and Quentin Williams

doi:10.1038/nature04311

See also: Editor's summary


Widespread amphibian extinctions from epidemic disease driven by global warming p161

J. Alan Pounds, Martín R. Bustamante, Luis A. Coloma, Jamie A. Consuegra, Michael P. L. Fogden, Pru N. Foster, Enrique La Marca, Karen L. Masters, Andrés Merino-Viteri, Robert Puschendorf, Santiago R. Ron, G. Arturo Sánchez-Azofeifa, Christopher J. Still and Bruce E. Young

doi:10.1038/nature04246

See also: Editor's summary | News and Views by Blaustein & Dobson


A quantitative protein interaction network for the ErbB receptors using protein microarrays p168

Richard B. Jones, Andrew Gordus, Jordan A. Krall and Gavin MacBeath

doi:10.1038/nature04177


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Letters

A magnetic reconnection X-line extending more than 390 Earth radii in the solar wind p175

T. D. Phan, J. T. Gosling, M. S. Davis, R. M. Skoug, M. Øieroset, R. P. Lin, R. P. Lepping, D. J. McComas, C. W. Smith, H. Reme and A. Balogh

doi:10.1038/nature04393

See also: Editor's summary | News and Views by Paschmann


A semiconductor source of triggered entangled photon pairs p179

R. M. Stevenson, R. J. Young, P. Atkinson, K. Cooper, D. A. Ritchie and A. J. Shields

doi:10.1038/nature04446


Ultrafast superheating and melting of bulk ice p183

H. Iglev, M. Schmeisser, K. Simeonidis, A. Thaller and A. Laubereau

doi:10.1038/nature04415

See also: Editor's summary


Methane emissions from terrestrial plants under aerobic conditions p187

Frank Keppler, John T. G. Hamilton, Marc Bras zlig and Thomas Röckmann

doi:10.1038/nature04420

See also: Editor's summary | News and Views by Lowe


Stability of hydrous melt at the base of the Earth's upper mantle p192

Tatsuya Sakamaki, Akio Suzuki and Eiji Ohtani

doi:10.1038/nature04352


A Cretaceous symmetrodont therian with some monotreme-like postcranial features p195

Gang Li and Zhe-Xi Luo

doi:10.1038/nature04168

See also: Editor's summary


Outbred embryos rescue inbred half-siblings in mixed-paternity broods of live-bearing females p201

Jeanne A. Zeh and David W. Zeh

doi:10.1038/nature04260

See also: Editor's summary


Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6 p204

Hans Häcker, Vanessa Redecke, Blagoy Blagoev, Irina Kratchmarova, Li-Chung Hsu, Gang G. Wang, Mark P. Kamps, Eyal Raz, Hermann Wagner, Georg Häcker, Matthias Mann and Michael Karin

doi:10.1038/nature04369

See also: Editor's summary


Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response p208

Gagik Oganesyan, Supriya K. Saha, Beichu Guo, Jeannie Q. He, Arash Shahangian, Brian Zarnegar, Andrea Perry and Genhong Cheng

doi:10.1038/nature04374

See also: Editor's summary


Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts p212

Alexander Meissner and Rudolf Jaenisch

doi:10.1038/nature04257

See also: Editor's summary | News and Views by Weissman


Embryonic and extraembryonic stem cell lines derived from single mouse blastomeres p216

Young Chung, Irina Klimanskaya, Sandy Becker, Joel Marh, Shi-Jiang Lu, Julie Johnson, Lorraine Meisner and Robert Lanza

doi:10.1038/nature04277

See also: Editor's summary | News and Views by Weissman


Planar cell polarity signalling couples cell division and morphogenesis during neurulation p220

Brian Ciruna, Andreas Jenny, Diana Lee, Marek Mlodzik and Alexander F. Schier

doi:10.1038/nature04375

See also: Editor's summary


A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates p225

Daniel F. Jarosz, Veronica G. Godoy, James C. Delaney, John M. Essigmann and Graham C. Walker

doi:10.1038/nature04318


Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk p229

Peijian Zou, Nikos Pinotsis, Stephan Lange, Young-Hwa Song, Alexander Popov, Irene Mavridis, Olga M. Mayans, Mathias Gautel and Matthias Wilmanns

doi:10.1038/nature04343


Structure of the Sec13/31 COPII coat cage p234

Scott M. Stagg, Cemal Gürkan, Douglas M. Fowler, Paul LaPointe, Ted R. Foss, Clinton S. Potter, Bridget Carragher and William E. Balch

doi:10.1038/nature04339


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Naturejobs

Prospect

The best-laid plans p239

Planning should take into account the unexpected.

Paul Smaglik

doi:10.1038/nj7073-239a


Career Views

Miodrag Stojkovic, deputy director of regenerative medicine, Prince Felipe Research Centre, Valencia, Spain p240

Leading stem-cell biologist heads across Europe.

Siëlle Gramser

doi:10.1038/nj7073-240a


Mentors & Protégés p240

Physics student praises mentor for good career guidance.

Timothy Stoltzfus-Dueck

doi:10.1038/nj7073-240b


Alumnus Journal: Writing up p240

Finishing a thesis can be worrisome and wonderful.

Sidney Omelon

doi:10.1038/nj7073-240c


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Futures

Printcrime p242

Copy this story.

Cory Doctorow

doi:10.1038/439242a


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