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Editorials

Preparing for disaster p889

Earth scientists should find better mechanisms to disseminate facts about the risks of natural disasters, to help local populations make the necessary preparations.

doi:10.1038/438889a


Europe's right stuff p889

The European Space Agency is making good use of its funds for space exploration.

doi:10.1038/438889b


Wiki's wild world p890

Researchers should read Wikipedia cautiously and amend it enthusiastically.

doi:10.1038/438890a


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Research Highlights

Research highlights p892

doi:10.1038/438892a


Correction p893

doi:10.1038/438893a


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News

Big money for cancer genomics p894

NIH announces first phase of ambitious project.

Erika Check

doi:10.1038/438894a


Developing nations offer hope in climate talks p895

Montreal conference is a qualified success.

Amanda Haag

doi:10.1038/438895a


Fake pottery buries theory of early start for Christianity p895

Dutch artefacts are not what they seem.

Siëlle Gramser

doi:10.1038/438895b


Sidelines p896

doi:10.1038/438896a


Budget boost gets Russia back in the space game p896

Oil revenues help to relaunch Soviet missions.

Tony Reichhardt

doi:10.1038/438896b


Pokémon blocks gene name p897

Moniker proves too much for games company.

Tom Simonite

doi:10.1038/438897a


Snapshot: Blot on the landscape p899

Satellite snaps smoke plume over Britain.

doi:10.1038/438899a


Journal grows suspicious of Vioxx data p899

Editors express concern over paper's conclusions.

Meredith Wadman

doi:10.1038/438899b


Internet encyclopaedias go head to head p900

Jimmy Wales' Wikipedia comes close to Britannica in terms of the accuracy of its science entries, a Nature investigation finds.

Jim Giles

doi:10.1038/438900a


News in brief p902

doi:10.1038/438902a


Correction p902

doi:10.1038/438902b


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News Features

Natural disasters: The chaos to come p903

Natural disasters have wreaked havoc on the planet in the past twelve months, and some say that things will only get worse. Quirin Schiermeier assesses the world's growing vulnerability to catastrophe.

doi:10.1038/438903a

See also: Editor's summary


Natural disasters: The vanishing coast p908

In the wake of Hurricane Katrina, coastal experts are trying to gauge the destruction to Louisiana's marshes. Emma Marris travels to the coast to learn what might be saved — and what might not.

doi:10.1038/438908a


Natural disasters: Roots of recovery p910

Replanting coastal forests destroyed by last December's tsunami sounds like a good idea — especially if they protect against future storms. But such plans need nurturing if they are to succeed, Erika Check discovers.

doi:10.1038/438910a


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Business

Olympus finds market rival hard to swallow p913

Imaging giant finally unveils its capsule endoscope.

Ichiko Fuyuno

doi:10.1038/438913a


In brief p913

doi:10.1038/438913b


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Correspondence

Biodiversity: there's a role to be played by 'museum-keepers' too p914

Swen C. Renner

doi:10.1038/438914a


Climate research opponent is not a friend to science p914

William P. Reich

doi:10.1038/438914b


Languages: Europe puts its money where its mouth is p914

Stephen C. Levinson

doi:10.1038/438914c


Languages: land may speak louder than words p914

Michael Stocker

doi:10.1038/438914d


Taxing question of when ethics go up in smoke p914

Johannes Gerdes

doi:10.1038/438914e


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Books and Arts

Changing your world view p915

Software that turns maps into landscapes reveals how cultural baggage can disort scientific images.

Philip Ball reviews Landscapes Without Memory by Joan Fontcuberta

doi:10.1038/438915a


Taking flight p916

Richard Grimmett reviews Birds of South Asia: The Ripley Guide by Pamela C. Rasmussen and John C. Anderton

doi:10.1038/438916a


Tracing the history of art p916

David G. Stork reviews Optics, Instruments and Painting, 1420–1720: Reflections on the Hockney–Falco Thesis [Early Science and Medicine Vol. 10 no. 2]

doi:10.1038/438916b


Theatre: Self deception p917

Lucy Odling-Smee reviews On Ego

doi:10.1038/438917a


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Essay

Concept

An asymmetric world p919

At the level of particles, things can happen in reverse, because particles obey time-symmetric laws of mechanics. But then why does matter, which is made up of these building blocks, behave irreversibly?

Oliver Penrose

doi:10.1038/438919a


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News and Views

Archaeology: Life on the Costa del Cromer p921

Flint fragments from eastern England constitute the earliest known evidence of human occupation of Britain. The climate was balmy, and the environment was home to a wide range of animals and plants.

Wil Roebroeks

doi:10.1038/438921a

See also: Editor's summary


Fluid dynamics: Drat such custard! p922

The mixing of festive sweetmeats and the stirring of cream into coffee are toothsome examples of the irreversibility of physical processes. In certain systems, however, the concept gets its just desserts.

Troy Shinbrot

doi:10.1038/438922a

See also: Editor's summary


Neuroscience: A painful factor p923

Peripheral nerve injury activates cells in the spinal cord called microglia. But how do such cells cause the ensuing chronic pain? It seems that they release a small protein that disrupts normal inhibition of pain signalling.

Carole Torsney and Amy B. MacDermott

doi:10.1038/438923a

See also: Editor's summary


50 & 100 years ago p924

doi:10.1038/438924a


Earth science: Volte-face in the Punjab p925

Rivers are the great conveyor belts that carry sediment from mountains to the sea. In the Punjab — the Land of Five Rivers — a wholesale shift occurred in the past that re-routed sediment to different oceans.

Philip A. Allen

doi:10.1038/438925a


Microbiology: Perspectives on plague p926

Helen Dell

doi:10.1038/438926a

See also: Editor's summary


Developmental biology: A message to the back side p926

Vertebrate embryos from fish to mammals seem to use different routes to work out which way is up and which side is front. Yet a novel system involved in defining the dorsal side of fish might be conserved in mammals.

Wolfgang Driever

doi:10.1038/438926b


Obituary: Richard Southwood (1931–2005) p928

Entomologist, ecologist and science policy adviser.

Charles Godfray and Michael Hassell

doi:10.1038/438928a


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Brief Communications

Post-spawning egg care by a squid p929

Spying on a brooding deep-sea squid reveals that it cradles and aerates its eggs while they mature.

Brad A. Seibel, Bruce H. Robison and Steven H. D. Haddock

doi:10.1038/438929a

See also: Editor's summary


Colloid science: Non-spherical bubbles p930

Anand Bala Subramaniam, Manouk Abkarian, L. Mahadevan and Howard A. Stone

doi:10.1038/438930a

See also: Editor's summary


Erratum: Nanoscale hydrodynamics: Enhanced flow in carbon nanotubes p930

Mainak Majumder, Nitin Chopra, Rodney Andrews and Bruce Hinds

doi:10.1038/438930b


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Brief Communications Arising

Seismology: Tectonic strain in plate interiors? pE9

E. Calais, G. Mattioli, C. DeMets, J. -M. Nocquet, S. Stein, A. Newman and P. Rydelek

doi:10.1038/nature04428


Seismology: Tectonic strain in plate interiors? (Reply) pE10

R. Smalley, Jr, M. A. Ellis, J. Paul and R. B. Van Arsdale

doi:10.1038/nature04429


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Insight: Angiogenesis

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Insight: Angiogenesis

Angiogenesis p931

Natalie DeWitt

doi:10.1038/438931a


Angiogenesis in life, disease and medicine p932

Peter Carmeliet

doi:10.1038/nature04478


Endothelial cells and VEGF in vascular development p937

Leigh Coultas, Kallayanee Chawengsaksophak and Janet Rossant

doi:10.1038/nature04479


Lymphangiogenesis in development and human disease p946

Kari Alitalo, Tuomas Tammela and Tatiana V. Petrova

doi:10.1038/nature04480


From angiogenesis to neuropathology p954

David A. Greenberg and Kunlin Jin

doi:10.1038/nature04481


Retinal angiogenesis in development and disease p960

Ray F. Gariano and Thomas W. Gardner

doi:10.1038/nature04482


Angiogenesis as a therapeutic target p967

Napoleone Ferrara and Robert S. Kerbel

doi:10.1038/nature04483



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Articles

Probing ion-channel pores one proton at a time p975

Gisela D. Cymes, Ying Ni and Claudio Grosman

doi:10.1038/nature04293

See also: Editor's summary


Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis p981

Huijian Wu, Yupeng Chen, Jing Liang, Bin Shi, Ge Wu, Ying Zhang, Dan Wang, Ruifang Li, Xia Yi, Hua Zhang, Luyang Sun and Yongfeng Shang

doi:10.1038/nature04225

See also: Editor's summary


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Letters

The afterglow and elliptical host galaxy of the short bold gamma-ray burst GRB 050724 p988

E. Berger, P. A. Price, S. B. Cenko, A. Gal-Yam, A. M. Soderberg, M. Kasliwal, D. C. Leonard, P. B. Cameron, D. A. Frail, S. R. Kulkarni, D. C. Murphy, W. Krzeminski, T. Piran, B. L. Lee, K. C. Roth, D.-S. Moon, D. B. Fox, F. A. Harrison, S. E. Persson, B. P. Schmidt, B. E. Penprase, J. Rich, B. A. Peterson and L. L. Cowie

doi:10.1038/nature04238

See also: Editor's summary


An origin in the local Universe for some short bold gamma-ray bursts p991

N. R. Tanvir, R. Chapman, A. J. Levan and R. S. Priddey

doi:10.1038/nature04310

See also: Editor's summary


An origin for short bold gamma-ray bursts unassociated with current star formation p994

S. D. Barthelmy, G. Chincarini, D. N. Burrows, N. Gehrels, S. Covino, A. Moretti, P. Romano, P. T. O'Brien, C. L. Sarazin, C. Kouveliotou, M. Goad, S. Vaughan, G. Tagliaferri, B. Zhang, L. A. Antonelli, S. Campana, J. R. Cummings, P. D'Avanzo, M. B. Davies, P. Giommi, D. Grupe, Y. Kaneko, J. A. Kennea, A. King, S. Kobayashi, A. Melandri, P. Meszaros, J. A. Nousek, S. Patel, T. Sakamoto and R. A. M. J. Wijers

doi:10.1038/nature04392

See also: Editor's summary


Chaos and threshold for irreversibility in sheared suspensions p997

D. J. Pine, J. P. Gollub, J. F. Brady and A. M. Leshansky

doi:10.1038/nature04380

See also: Editor's summary | News and Views by Shinbrot


Reorganization of the western Himalayan river system after five million years ago p1001

Peter D. Clift and Jerzy Blusztajn

doi:10.1038/nature04379

See also: News and Views by Allen


Efficacy of the post-perovskite phase as an explanation for lowermost-mantle seismic properties p1004

James Wookey, Stephen Stackhouse, J-Michael Kendall, John Brodholt and G. David Price

doi:10.1038/nature04345


The earliest record of human activity in northern Europe p1008

Simon A. Parfitt, René W. Barendregt, Marzia Breda, Ian Candy, Matthew J. Collins, G. Russell Coope, Paul Durbidge, Mike H. Field, Jonathan R. Lee, Adrian M. Lister, Robert Mutch, Kirsty E. H. Penkman, Richard C. Preece, James Rose, Christopher B. Stringer, Robert Symmons, John E. Whittaker, John J. Wymer and Anthony J. Stuart

doi:10.1038/nature04227

See also: Editor's summary | News and Views by Roebroeks


A RhoGDP dissociation inhibitor spatially regulates growth in root hair cells p1013

Rachel J. Carol, Seiji Takeda, Paul Linstead, Marcus C. Durrant, Hana Kakesova, Paul Derbyshire, Sinéad Drea, Viktor Zarsky and Liam Dolan

doi:10.1038/nature04198


BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain p1017

Jeffrey A. M. Coull, Simon Beggs, Dominic Boudreau, Dominick Boivin, Makoto Tsuda, Kazuhide Inoue, Claude Gravel, Michael W. Salter and Yves De Koninck

doi:10.1038/nature04223

See also: Editor's summary | News and Views by Torsney & MacDermott


Heat activation of TRPM5 underlies thermal sensitivity of sweet taste p1022

Karel Talavera, Keiko Yasumatsu, Thomas Voets, Guy Droogmans, Noriatsu Shigemura, Yuzo Ninomiya, Robert F. Margolskee and Bernd Nilius

doi:10.1038/nature04248

See also: Editor's summary


Mapping stem cell activities in the feather follicle p1026

Zhicao Yue, Ting-Xin Jiang, Randall Bruce Widelitz and Cheng-Ming Chuong

doi:10.1038/nature04222

See also: Editor's summary


The zebrafish dorsal axis is apparent at the four-cell stage p1030

Aniket V. Gore, Shingo Maegawa, Albert Cheong, Patrick C. Gilligan, Eric S. Weinberg and Karuna Sampath

doi:10.1038/nature04184

See also: Editor's summary | News and Views by Driever


The Rae1–Nup98 complex prevents aneuploidy by inhibiting securin degradation p1036

Karthik B. Jeganathan, Liviu Malureanu and Jan M. van Deursen

doi:10.1038/nature04221

See also: Editor's summary


Towards complete cofactor arrangement in the 3.0 Å resolution structure of photosystem II p1040

Bernhard Loll, Jan Kern, Wolfram Saenger, Athina Zouni and Jacek Biesiadka

doi:10.1038/nature04224

See also: Editor's summary


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Naturejobs

Prospect

Same society, different rules p1045

Max Planck students try collective bargaining.

Paul Smaglik

doi:10.1038/nj7070-1045a


Region

Italy's bright spots p1046

Public funding problems have prevented Italy from catching up with other European scientific hubs. But some privately funded local initiatives show glimmers of hope. Quirin Schiermeier and Alison Abbott report.

Alison Abbott & Quirin Schiermeier

doi:10.1038/nj7070-1046a


Career Views

Graduate journal - Year-End Review: The longest year

Reflections on a tumultuous period of heartache, graduation, travels and renewal.

Jason Underwood

doi:10.1038/nj0104


Graduate journal - Year-End Review: An examination of conscience

Successes and setbacks mark the first year as a PhD student.

Karolina Tkaczuk

doi:10.1038/nj0105


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Futures

RAM shift phase 2 p1050

The Fourth Law, and beyond.

Greg Bear

doi:10.1038/4381050a


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