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News Feature
Nature 438, 726-728 (8 December 2005) | doi:10.1038/438726a; Published online 7 December 2005
Nonsense mutations: Running the red light
Claire Ainsworth1
- Claire Ainsworth is a senior News and Features editor for Nature.
Abstract
A trial drug encourages cells to ignore the signs that stop them making faulty proteins. Sound dangerous? Claire Ainsworth discovers that it could be a cure for genetic disease.
On 28 November, two patients in an Israeli hospital downed a vanilla-flavoured shake in the hope of curing their cystic fibrosis. The drug in the shake is meant to get their cells to ignore the genetic mutation that makes their lives a misery.
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