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Nature 438, 578-580 (1 December 2005) | doi:10.1038/nature04394; Published online 30 November 2005
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Gates Research Fellow Vacancy
- London School of Hygiene & Tropical Medicine
- London, UK
Professorship
- Friedrich-Alexander-Universitat Erlangen-Nurnberg
- Erlangen 91054 Germany
Introduction Membranes are more mosaic than fluid
Donald M. Engelman1
Abstract
The wealth of new data on membrane protein structures and functions is changing our general view of membrane architecture. Some of the key themes that are emerging are that membranes are patchy, with segregated regions of structure and function, that lipid regions vary in thickness and composition, and that crowding and ectodomains limit exposure of lipid to the adjacent aqueous regions.
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