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Nature 438, 569-570 (1 December 2005) | doi:10.1038/438569a; Published online 30 November 2005
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Head-Preclinical
- Syngene International
- Bangalore, Karnataka 560099 India
Tier II Canada Research Chair in Cellular Science and Human Health
- Concordia University
- Montreal, Quebec Canada
Cell biology: A greasy grip
Anthony G. Lee1
Abstract
How do the lipids and proteins of the cell membrane interact to create a functioning barrier for the cell? A high-resolution structure of a membrane protein reveals intimate contacts with its lipid neighbours.
The design of a biological membrane is beautifully simple: a lipid bilayer provides the basic barrier, and into this are plugged a variety of membrane proteins. Each protein is designed to carry out some particular function for the cell — moving specific molecules in or out of the cell, say, or sensing the environment.
- Anthony G. Lee is in the School of Biological Sciences, University of Southampton, Southampton SO16 7PX, UK.
Email: a.g.lee@soton.ac.co.uk
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