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Nature 438, 293-295 (17 November 2005) | doi:10.1038/438293a; Published online 16 November 2005
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Senior Scientist, Bioinformatics and Protein Design
- Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
- Copenhagen 2200 Denmark
Scientist, Disease Modeling & Simulation
- Philip Morris International (PMI)
- Neuchâtel, Switzerland
Epidemiology: Dimensions of superspreading
Alison P. Galvani1 & Robert M. May2
Abstract
Analyses of contact-tracing data on the spread of infectious disease, combined with mathematical models, show that control measures require better knowledge of variability in individual infectiousness.
The SARS epidemic was notable for the existence of 'superspreaders' who infected dozens of people, whereas other infectious individuals infected few or none. Were SARS superspreaders anomalies, or are superspreaders characteristic of most infectious diseases?
- Alison P. Galvani is in the Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Email: alison.galvani@yale.edu - Robert M. May is in the Department of Zoology, University of Oxford, Oxford OX1 3PS, UK.
Email: robert.may@zoo.ox.ac.uk
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