Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 437, 1247-1249 (27 October 2005) | doi:10.1038/4371247a; Published online 26 October 2005
Open Innovation Challenges
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
- More Challenges
- Powered by:
nature jobs
Postdoctoral Research Associate
- Rice University
- Houston, Texas, USA
Scientist (Bioinformatics)
- Polyclone Bioservices Pvt. Ltd
- Bangalore India
Cell biology: Helices sculpt membrane
Guillaume Drin1 & Bruno Antonny1
Abstract
Many proteins are carried within cells in bubble-like sacs. These are pinched off from membranes inside the cell, and it seems that the Sar1p protein is key in both starting and finishing this budding process.
The cell contains a network of membrane-bound compartments that exchange proteins with each other and with the cell surface thanks to several haulage systems, each providing a specific link between one station and another. At the departure point, specialized 'coat' proteins wrap up a small area of the lipid membrane, shaping it into a bulging 'bud' and gathering up proteins due to be transported inside it1.
- Guillaume Drin and Bruno Antonny are at the CNRS Institut de Pharmacologie Moléculaire et Cellulaire et Université de Nice, Sophia Antipolis, 06560 Valbonne, France.
Email: antonny@ipmc.cnrs.fr
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Surface versus Intracellular Polarization of Cortical CellsNature Letters to Editor (21 Oct 1967)
ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motifThe EMBO Journal Article (06 Jul 2005)
A general amphipathic α-helical motif for sensing membrane curvatureNature Structural & Molecular Biology Article (01 Feb 2007)
See all 6 matches for Research