Access
To read this story in full you will need to login or make a payment (see right).
Commentary
Nature 437, 1233-1234 (27 October 2005) | doi:10.1038/4371233a; Published online 26 October 2005
Open Innovation Challenges
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
- More Challenges
- Powered by:
nature jobs
Full-Professor of Heart and Thoracic Surgery (W3) (f / m)
- Friedrich-Schiller-University Jena
- Jena Germany
Business Devlopment Officer
- Rhydburg Pharmaceuticals
- Selaqui-Dehradun India
Deeper into the genome
Richard Gibbs1
- Richard Gibbs is at Baylor College of Medicine, Houston, Texas 77030, USA.
Abstract
The next large-scale human genome project after HapMap should catalogue inherited variation in the general population that directly affects gene function, argues Richard Gibbs.
The International HapMap Project has catalogued the patterns of more than 1 million single-base changes (known as single nucleotide polymorphisms, SNPs) in the genome sequences of 269 people drawn from four diverse human populations1. Most of these SNPs do not directly influence gene function, but the data provide valuable information about the overall pattern of chromosome organization and offer new tools for finding disease-causing genes in humans.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
