Supplementary information
From the following article:
Crystal structure of a junction between B-DNA and Z-DNA reveals two extruded bases
Sung Chul Ha, Ky Lowenhaupt, Alexander Rich, Yang-Gyun Kim & Kyeong Kyu Kim
Nature 437, 1183-1186(20 October 2005)
doi:10.1038/nature04088
Supplementary Discussion
Additional discussion on the results of the study that could not be included in the main text.
Supplementary Methods
Additional details on the methods used in the study that could not be included in the main text.
Supplementary Tables
Supplementary Table 1: Data collection phasing and refinement statistics. Supplementary Table 2: Local base pair step parameters of B-Z DNA and standard B- and Z-DNA. Supplementary Table 3 RMS deviation (Å) among Z
domains.
Supplementary Figure S1
Overall structure of the B-Z junction containing DNA bound to hZADAR1.
Supplementary Figure S2
Structural overlap of the Z proteins bound to Z-DNA.
Supplementary Figure S3
Titration by CD spectrometry of the 17mer duplex with hZADAR1.
Supplementary Figure S4
Stereo 2Fo-Fc omit maps of extruded nucleotides.
Supplementary Figure S5
A diagram illustrating the B-Z transition and the ensuing conformational changes.
Supplementary Figure S6
Structures of DNA including extruded bases.
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