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News and Views
Nature 437, 1097-1098 (20 October 2005) | doi:10.1038/4371097a; Published online 19 October 2005
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Postdoctoral Fellow - Computational Genomics - Team 78 – Ref: 80464
- Wellcome Trust Sanger Institute
- Hinxton, Cambridgeshire CB10 1, UK
Senior Statistical Genetics in High-throughput Sequencing Analysis
- University of Oxford
- Oxford United Kingdom
Molecular biology: DNA twists and flips
Richard R. Sinden1
Abstract
DNA can shape itself into many forms to achieve its purposes in life. The crystal structure of the junction between two of its forms provides insight into how DNA might accomplish some of these acrobatics.
Crick and Watson's famous structure of DNA has become an icon of our age, somewhat eclipsing DNA's other structural forms. Imagine unravelling the familiar helix (termed B-DNA) and then twisting it up the other way around.
- Richard R. Sinden is in the Laboratory of DNA Structure and Mutagenesis, Center for Genome Research, Institute of Biosciences and Technology, Texas A&M University System Health Science Center, 2121 West Holcombe Boulevard, Houston, Texas 77030-3303, USA.
Email: rsinden@ibt.tamhsc.edu
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