FIGURE 4. RNA recognition by RNase E catalytic domain.
From the following article:
Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover
Anastasia J. Callaghan, Maria Jose Marcaida, Jonathan A. Stead, Kenneth J. McDowall, William G. Scott and Ben F. Luisi
Nature 437, 1187-1191 (20 October 2005)
doi: 10.1038/nature04084
a, An overlay of RNase E tetramer in complex with bound 10-mer (magenta), 13-mer (green) and 15-mer (violet) RNA. Catalytic residues (red) and 5' sensor pocket (gold) in space-filling representation. The 15-mer RNA extends away from the principal dimer into a symmetry-related tetramer (semi-transparent beige) and, reciprocally, from the symmetry-related tetramer (semi-transparent violet) back into the principal dimer (beige). Only one active site with RNA bound is shown for simplicity. b, RNase E bound to an RNA hairpin model (violet) extrapolated from the RNase E/15-mer RNA complex crystal structure.
