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Nature 437, 821 (6 October 2005) | doi:10.1038/437821a; Published online 5 October 2005

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Microbiology: Loading the type III cannon

Bill Blaylock1 & Olaf Schneewind1

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Many pathogenic bacteria possess a secretion machine that shoots noxious proteins into host cells. But the ammunition is larger than the bore of the bacterial gun, so how is it fed into the machine?

Bacteria and the organisms they parasitize are engaged in a constant struggle. Each side possesses a veritable arsenal of weapons and defensive countermeasures.

  1. Bill Blaylock and Olaf Schneewind are in the Department of Microbiology, University of Chicago, 920 East 58th Street, Chicago, Illinois 60637, USA.
    Email: oschnee@bsd.uchicago.edu

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