Figures and Tables

From the following article:

Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme

Luke J. Higgins, Feng Yan, Pinghua Liu, Hung-wen Liu & Catherine L. Drennan

Nature 437, 838-844(1 October 2005)

doi:10.1038/nature03924

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Figure 1

Fosfomycin biosynthesis.

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Figure 2

Overall structure of Fe(ii)-HppE.

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Figure 3

HppE active sites displayed with 2Fo - Fc maps contoured from 1.0–1.5sigma.

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Figure 4

Structural insights into catalysis.

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Figure 5

Schematic of interactions of bidentate-bound S-HPP with protein, water and Fe(ii).

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Figure 6

Possible mechanisms for HppE.

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