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Nature 437, 326-327 (15 September 2005) | doi:10.1038/437326a; Published online 14 September 2005

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Genomics: Massively parallel sequencing

Yu-Hui Rogers1 & J. Craig Venter1

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A sequencing system has been developed that can read 25 million bases of genetic code — the entire genome of some fungi — within four hours. The technique may provide an alternative approach to DNA sequencing.

Since the publication of the first complete genome sequence of a living organism1 in 1995, the field of genomics has changed dramatically. Fuelled by innovations in high-throughput DNA sequencing, high-performance computing and bioinformatics, genomic science has expanded substantially and the rate of genomic discovery has grown exponentially.

  1. Yu-Hui Rogers and J. Craig Venter are at the J. Craig Venter Institute, 9704 Medical Center Drive, Rockville, Maryland 20850, USA.
    Email: jcventer@venterinstitute.org

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