Supplementary information

From the following article:

Strategies for containing an emerging influenza pandemic in Southeast Asia

Neil M. Ferguson, Derek A.T. Cummings, Simon Cauchemez, Christophe Fraser, Steven Riley, Aronrag Meeyai, Sopon Iamsirithaworn & Donald S. Burke

Nature 437, 209-214(8 September 2005)

doi:10.1038/nature04017

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Supplementary Notes

Provides details of model structure, parameter estimation and sensitivity analyses undertaken.

Supplementary Video S1

Example of baseline simulated pandemic emergence in Thailand (R0=1.5). Greyscale represents population density of susceptibles (on logarithmic scale), red represents areas with infected individuals, and green represents areas which have recovered from infection. The video shows 300 days of spread.

Supplementary Video S2

Example of successful containment of emergent pandemic influenza. Simulation shown assumes R0=1.8 and implementation of a social+5km radial prophylaxis policy combined with 5km area quarantine (see main text). Colours as for Supplementary Video 1, except blue represents areas in which treatment is occurring. The video shows 100 days of spread.

Supplementary Video S3

Example of containment failure due to single-country policy implementation. Simulation shown assumes R0=1.7 and implementation in Thailand only of a social+5km radial prophylaxis policy combined with 5km radial closure of 90% of schools and 50% of workplaces (see main text). Colours as for Supplementary Video 2. The video shows 300 days of spread.

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