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Nature 437, 199-201 (8 September 2005) | doi:10.1038/437199a; Published online 7 September 2005

Evolutionary genetics: Microarrays and species origins

Roger Butlin1 & Cally Roper2

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Whole-genome arrays have been used to reveal small islands of genetic differentiation in Anopheles mosquitoes. Analysis of these regions will identify genes involved in the initial stages of speciation.

What are the genetic modifications that underlie the first steps in the origin of new species? The use of microarrays to make whole-genome comparisons between populations that can interbreed, but only to a limited degree, provides a fresh approach to the question.

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