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Nature 437, E3 (8 September 2005) | doi:10.1038/nature04178; Published online 7 September 2005

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Malaria risk: Estimating clinical episodes of malaria

Bernard L. Nahlen1, Eline L. Korenromp1, John M. Miller1 & Kenji Shibuya2

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Arising from: R. W. Snow, C. A. Guerra, A. M. Noor, H. Y. Myint & S. I. Hay Nature 434, 214–217 (2005); see also communication from Bell; Snow et al. reply.

Estimates of the disease burden caused by malaria are crucial for informing malaria control programmes. Snow and colleagues claim that their estimate of 515 million cases of malaria caused by Plasmodium falciparum globally is up to 50% higher than that reported by the World Health Organization (WHO), and 200% higher for areas outside Africa1. However, this comparison refers to the WHO's estimates from 1990 and 1998, and not to the range of 300 million to 500 million that the WHO has used since 2000 (ref. 2). Both groups agree that the burden of malaria disease outside Africa, especially in South Asia, is greater than was estimated in the 1990s.

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