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Nature 437, 198-199 (8 September 2005) | doi:10.1038/437198a; Published online 7 September 2005
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Senior Scientist, Bioinformatics and Protein Design
- Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
- Copenhagen 2200 Denmark
Post-doctoral Research in Super-Resolution imaging of Mitotic Processes.
- Samuel Lunenfeld Research Institute
- Toronto, ON Canada
Biological physics: Rare returns on lost effort
Abstract
How does the size of a system affect its thermodynamic irreversibility? A deft experiment that observes the unfolding and refolding of a single molecule of RNA provides insights into the question at a small scale.
When vigorously stirred, a cup of coffee will heat up; a cup of hot coffee, however, will never stir a spoon (Fig. 1).
- Wesley P. Wong and Evan Evans are in the Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, Massachusetts 02215, USA. Wesley P. Wong is also in the Department of Physics, Harvard University, 17 Oxford Street, Cambridge, Massachusetts 02138, USA.
Email: wesley@physics.harvard.edu; Email: evanse@bu.edu
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RESEARCH
Verification of the Crooks fluctuation theorem and recovery of RNA folding free energiesNature Letters to Editor (08 Sep 2005)
