Supplementary information
From the following article:
Initial sequence of the chimpanzee genome and comparison with the human genome
The Chimpanzee Sequencing and Analysis Consortium
Nature 437, 69-87(1 September 2005)
doi:10.1038/nature04072
Supplementary Figures
Supplementary Figures S1-S12 and accompanying legends.
Supplementary Notes S1
Genome Sequencing and Assembly. Detailed description of chimpanzee DNA and cell-line resources; genome sequencing and assembly methods; assembly quality control; additional discussion. Supplementary Tables S1-S17.
Supplementary Notes S2
Genome Evolution. Additional methods and discussion related to nucleotide substitution rates, insertions/deletions, transposable elements and large-scale rearrangements. Supplementary Tables S18, S20-S22.
SupplementaryTable S19
Human- and chimpanzee-specific retrotransposed pseudogenes
Supplementary Notes S3
Gene Evolution. Additional methods and discussion related to evolutionary rates for protein coding genes, selective constraints, relative rate tests and genetic changes with potential phenotypic effects. Supplementary Tables S25, S27, S29, S31-S42, S44.
Supplementary Table S23
Rate estimates and additional information for each human-chimpanzee orthologue pair examined.
Supplementary Table S24
Rate estimates and additional information for each human-chimpanzee-mouse-rat orthologue quadruplet examined.
Supplementary Table S26
Absolute rate acceleration test statistics for each GO category.
SupplementaryTable S28
Absolute rate acceleration test statistics (non-parametric) for each GO category.
Supplementary Table S30
Relative rate acceleration test statistics for each GO category.
Supplementary Table S43
Putative human disease alleles present in chimpanzee, and status of support in the literature.
Supplementary Notes S4
Human Population Genetics. Additional methods and discussion related to assignment of ancestral alleles, and detection of selective sweeps in recent human evolution.
Supplementary Notes S5
Additional References. References cited in the Supplementary Notes.
Corrigendum
This file contains details regarding an error in Supplementary Table 24 at the time of publication.
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