Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 436, 1094-1095 (25 August 2005) | doi:10.1038/4361094a; Published online 24 August 2005
Open Innovation Challenges
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
-
Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
- More Challenges
- Powered by:
nature jobs
Chocolate Food Technologists
- Nestlé
- Broc, Switzerland
Fellowships
- Brighams and Women's Hospital
- Boston, MA
Biological chemistry: Just add chlorine
Nathan A. Schnarr1 & Chaitan Khosla1
Abstract
Nature provides lessons about developing 'green chemistry' in seemingly out-of-the-way places. One such lesson comes from an enzymatic step in the production of a leaf toxin by a bacterium.
As they describe on page 1191 of this issue1, a group of researchers led by Christopher Walsh has identified how chlorine is attached enzymatically to an intermediate during the formation of a natural product. This is not surprising in itself — the significance lies in the unreactive nature of the carbon centre concerned.
- Nathan A. Schnarr and Chaitan Khosla are in the Departments of Chemistry and Chemical Engineering, Stanford University, Stanford, California 94305-5025, USA.
Email: khosla@stanford.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Organometallic chemistry Charting the course of catalysisNature News and Views (18 Jun 2009)
RESEARCH
Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesisNature Letters to Editor (25 Aug 2005)
Two interconverting Fe( IV ) intermediates in aliphatic chlorination by the halogenase CytC3Nature Chemical Biology Letter (01 Feb 2007)
Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesisNature Letters to Editor (16 Mar 2006)
See all 5 matches for Research