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From the following article:

Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2

Mauro Costa-Mattioli, Delphine Gobert, Heather Harding, Barbara Herdy, Mounia Azzi, Martin Bruno, Michael Bidinosti, Cyrinne Ben Mamou, Edwige Marcinkiewicz, Madoka Yoshida, Hiroaki Imataka, A. Claudio Cuello, Nabil Seidah, Wayne Sossin, Jean-Claude Lacaille, David Ron, Karim Nader & Nahum Sonenberg

Nature 436, 1166-1173(25 August 2005)

doi:10.1038/nature03897

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Figure 1

Unusual properties of LTP induced in slices from GCN2-/- mice.

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Figure 2

ATF4 mRNA translation is downregulated in GCN2-/- mice.

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Figure 3

GCN2-/- mice are impaired in contextual but not auditory fear conditioning.

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Figure 4

Long-term spatial memory of GCN2-/- mice is enhanced after weak training but impaired after more intense training (in the Morris water maze).

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