Supplementary information

From the following article:

Exotoxin A–eEF2 complex structure indicates ADP ribosylation by ribosome mimicry

René Jørgensen, A. Rod Merrill, Susan P. Yates, Victor E. Marquez, Adrian L. Schwan, Thomas Boesen & Gregers R. Andersen

Nature 436, 979-984(18 August 2005)

doi:10.1038/nature03871

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Supplementary Figure Legends

Legends to accompany Supplementary Figures S1-S3.

Supplementary Figure S1

Electron densities for TAD, the ADP-ribosylation, and PJ34.

Supplementary Figure S2

Cartoon representations of the four toxin targets G s, RhoA, Actin and G i showing the positions of the ADP-ribosylated residues and the proposed Asp696 (D) and diphthamide (DA) analogues.

Supplementary Figure S3

A putative function of the diphthamide in translocation.

Supplementary Table S1

Statistics for data collection and refinement of the two structures.

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