Figures and Tables

From the following article:

Challenges and successes in developing new therapies for hepatitis C

Raffaele De Francesco & Giovanni Migliaccio

Nature 436, 953-960(18 August 2005)

doi:10.1038/nature04080

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

The structures of inhibitors BILN 2061 and VX-950 and of the NS3 serine protease domain (green) complexed with the central domain of NS4A (red).

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Figure 2

Examples of inhibitors of the HCV RNA-dependent RNA polymerase.

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Figure 3

The crystal structure of the NS5B RNA-dependent RNA polymerase.

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Table 1

A sample of the drug pipeline for hepatitis C

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