Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 436, 787-789 (11 August 2005) | doi:10.1038/436787a; Published online 10 August 2005
Open Innovation Challenges
-
Protect Enzyme from In Planta Degradation
A proposal for stable expression of an enzyme in corn seed is desired.
-
Efficient Chromosome Doubling: Plant Cell Division
The Seeker is looking for an efficient chromosome doubling method in plants and in particular, metho...
- More Challenges
- Powered by:
nature jobs
Principal / Senior Scientist- Neurosciences
- Genentech
- South San Francisco, CA, USA
Postdoctoral Position in Cystic Fibrosis / Pulmonary Research
- Universitatsklinikum Heidelberg
- Heidelberg 69120 Germany
Cancer: Two in one
Anton Berns1
Abstract
As cancer develops, at least two cell processes are disrupted — cell growth is promoted, and cell death inhibited. It seems that mutated versions of the notorious cancer-promoting protein MYC can accomplish both at once.
The MYC gene is one of the classic cancer-promoting 'oncogenes'. It is overexpressed in many types of tumour, and the MYC protein it encodes causes a surge in the proliferation of cells.
- Anton Berns is in the Division of Molecular Genetics and Centre for Biomedical Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.
Email: a.berns@nki.nl
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
p38 Mitogen-Activated Protein Kinase Inhibitor Protects the Epidermis Against the Acute Damaging Effects of Ultraviolet Irradiation by Blocking Apoptosis and Inflammatory ResponsesJournal of Investigative Dermatology Original Article
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutantsNature Article (11 Aug 2005)
Probing tumor phenotypes using stable and regulated synthetic microRNA precursorsNature Genetics Technical Report (01 Nov 2005)
See all 6 matches for Research