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Editorials

All together now p303

The decision to site the fusion experiment ITER in France left relatively little bad blood between the international partners, who must now rally behind the project.

doi: 10.1038/436303a


Socialism in one country p303

Cuba's scientific community has made substantial progress in addressing social problems.

doi: 10.1038/436303b


Agency under siege p304

Conflicts-of-interest at the US National Institutes of Health justify the agency's ethics crackdown.

doi: 10.1038/436304a


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Research Highlights

Research highlights p306

doi: 10.1038/436306a


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News

Psychologists warn of more suicide attacks in the wake of London bombs p308

Terror threat to the West 'will remain high for years to come', says analyst.

Jim Giles and Michael Hopkin

doi: 10.1038/436308a


Altered embryos offered as solution to stem-cell rift p309

Senators seek way out of voting dilemma.

Erika Check

doi: 10.1038/436309a


Bird flu: crossing borders p310

Despite recent reports from governments that bird flu is under control, it continues to spread through Asia's poultry and claim lives — there are even signs of human-to-human transmission. Declan Butler tracks the disease's inexorable spread.

doi: 10.1038/436310a


Arsenic-free water still a pipedream p313

Decontamination plants fail to free millions from poisoned supply.

Philip Ball

doi: 10.1038/436313a


Malaysia plans 'red book' in its attempts to go green p313

Biodiversity catalogue marks shift in attitude.

David Cyranoski

doi: 10.1038/436313b


Asia squeezes Europe's lead in science p314

Global share of scientific output rises in the East.

Andreas von Bubnoff

doi: 10.1038/436314a


Sidelines p315

doi: 10.1038/435315b


Animal-rights group sues over 'disturbing' work on sea lions p315

Conservation effort criticized for branding pups.

Rex Dalton

doi: 10.1038/436315a


News in brief p316

doi: 10.1038/436316a


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News Features

Fusion energy:  Just around the corner p318

For 50 years, physicists have been promising that power from nuclear fusion is imminent. Now they are poised to build an experiment that could vindicate their views. But will the machine work? Geoff Brumfiel investigates.

doi: 10.1038/436318a

See also: Editor's summary


Cuban science:  ¿Vive la revolución? p322

Cuba's socialist science policies are producing top-notch research from scant economic resources. But, as Jim Giles reports, they have harsh consequences for scientists who do not fit in with government priorities.

doi: 10.1038/436322a


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Business

Pumping up the volume p326

The business of writing popular science books is hard to break into — and even harder to make money out of. Tony Reichhardt reports.

doi: 10.1038/436326a


In brief p327

doi: 10.1038/436327a


Market watch p327

Quirin Schiermeier

doi: 10.1038/436327b


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Correspondence

Unlike climate science, GM is full of uncertainties p328

Douglas Parr

doi: 10.1038/436328a


Leave GM analysis to the relevant scientists p328

Denis Couvet

doi: 10.1038/436328b


Compensation for climate change must meet needs p328

W. Neil Adger and Jon Barnett

doi: 10.1038/436328c


There's more to a colourful life than simply sex p328

Paul Kenton

doi: 10.1038/436328d


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Books and Arts

Letters from a hero p329

What made Richard Feynman so much more than a Nobel prizewinning physicist?

Peter Galison reviews Perfectly Reasonable Deviations from the Beaten Track: The Letters of Richard P. Feynman

doi: 10.1038/436329a


Darwin's first love p330

Martin Rudwick reviews Charles Darwin, Geologist by Sandra Herbert

doi: 10.1038/436330a


Documentary:  In the right place at the right time p331

Henry Gee

doi: 10.1038/436331a

See also: Editor's summary


Science in culture: A trick of the tiles p332

Penrose tiling is realized on a huge scale in Perth to give a perceptual feast for the eyes.

Martin Kemp

doi: 10.1038/436332a

See also: Editor's summary


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News and Views

Palaeoclimate:  Foreshadowing the glacial era p333

Under what circumstances do glaciations persist or occur only transiently? Indications that short-lived 'icehouse' conditions occurred during the otherwise warm Eocene provide further cause for debate on the question.

Lee R. Kump

doi: 10.1038/436333a

See also: Editor's summary


Behavioural genetics:  Sex in fruitflies is fruitless p334

The courtship rituals of fruitflies are disrupted by mutations in the fruitless gene. A close look at the gene's products — some of which are sex-specific — hints at the neural basis of the flies' behaviour.

Charalambos P. Kyriacou

doi: 10.1038/436334a

See also: Editor's summary


Asteroids:  Shaken on impact p335

A single recent impact may have modified the craters on the asteroid Eros into the pattern we see today. This finding has implications for how we view the structure of asteroids — and for addressing any hazards they present.

Erik Asphaug

doi: 10.1038/436335a

See also: Editor's summary


50 and 100 years ago p336

doi: 10.1038/436336a


Metabolism:  A is for adipokine p337

Adipokines are hormones that signal changes in fatty-tissue mass and energy status so as to control fuel usage. A fat-derived adipokine that binds to vitamin A provides a new link between obesity and insulin resistance.

Deborah M. Muoio and Christopher B. Newgard

doi: 10.1038/436337a

See also: Editor's summary


Parasitology:  Triple genome triumph p337

Declan Butler

doi: 10.1038/436337b


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Brief Communications

Radiocarbon dating:  Jewish inspiration of Christian catacombs p339

A Jewish cemetery in ancient Rome harbours a secret that bears on the history of early Christianity.

Leonard V. Rutgers, Klaas van der Borg, Arie F. M. de Jong and Imogen Poole

doi: 10.1038/436339a

See also: Editor's summary


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Brief Communications Arising

Palaeoclimatology:  Formation of Precambrian sediment ripples pE1

Douglas J. Jerolmack and David Mohrig

doi: 10.1038/nature04025


Palaeoclimatology:  Formation of Precambrian sediment ripples (reply) pE1

Philip Allen and Paul Hoffman

doi: 10.1038/nature04026


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Articles

Eocene bipolar glaciation associated with global carbon cycle changes p341

Aradhna Tripati, Jan Backman, Henry Elderfield and Patrizia Ferretti

doi: 10.1038/nature03874

See also: Editor's summary


Neural crest origins of the neck and shoulder p347

Toshiyuki Matsuoka, Per E. Ahlberg, Nicoletta Kessaris, Palma Iannarelli, Ulla Dennehy, William D. Richardson, Andrew P. McMahon and Georgy Koentges

doi: 10.1038/nature03837

See also: Editor's summary


Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes p356

Qin Yang, Timothy E. Graham, Nimesh Mody, Frederic Preitner, Odile D. Peroni, Janice M. Zabolotny, Ko Kotani, Loredana Quadro and Barbara B. Kahn

doi: 10.1038/nature03711

See also: Editor's summary


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Letters

Extreme collisions between planetesimals as the origin of warm dust around a Sun-like star p363

Inseok Song, B. Zuckerman, Alycia J. Weinberger and E. E. Becklin

doi: 10.1038/nature03853

See also: Editor's summary


Seismic resurfacing by a single impact on the asteroid 433 Eros p366

P. C. Thomas and Mark S. Robinson

doi: 10.1038/nature03855

See also: Editor's summary


Massively parallel manipulation of single cells and microparticles using optical images p370

Pei Yu Chiou, Aaron T. Ohta and Ming C. Wu

doi: 10.1038/nature03831

See also: Editor's summary


Direct observation of electron dynamics in the attosecond domain p373

A. Föhlisch, P. Feulner, F. Hennies, A. Fink, D. Menzel, D. Sanchez-Portal, P. M. Echenique and W. Wurth

doi: 10.1038/nature03833


Spin transition of iron in magnesiowüstite in the Earth's lower mantle p377

Jung-Fu Lin, Viktor V. Struzhkin, Steven D. Jacobsen, Michael Y. Hu, Paul Chow, Jennifer Kung, Haozhe Liu, Ho-kwang Mao and Russell J. Hemley

doi: 10.1038/nature03825


The long-term strength of Europe and its implications for plate-forming processes p381

M. Pérez-Gussinyé and A. B. Watts

doi: 10.1038/nature03854

See also: Editor's summary


Reinforcement of pre-zygotic isolation and karyotype evolution in Agrodiaetus butterflies p385

Vladimir A. Lukhtanov, Nikolai P. Kandul, Joshua B. Plotkin, Alexander V. Dantchenko, David Haig and Naomi E. Pierce

doi: 10.1038/nature03704

See also: Editor's summary


Deep sub-seafloor prokaryotes stimulated at interfaces over geological time p390

R. John Parkes, Gordon Webster, Barry A. Cragg, Andrew J. Weightman, Carole J. Newberry, Timothy G. Ferdelman, Jens Kallmeyer, Bo B. Jørgensen, Ivano W. Aiello and John C. Fry

doi: 10.1038/nature03796

See also: Editor's summary


Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour p395

Devanand S. Manoli, Margit Foss, Adriana Villella, Barbara J. Taylor, Jeffrey C. Hall and Bruce S. Baker

doi: 10.1038/nature03859

See also: Editor's summary


EphrinB2 is the entry receptor for Nipah virus, an emergent deadly paramyxovirus p401

Oscar A. Negrete, Ernest L. Levroney, Hector C. Aguilar, Andrea Bertolotti-Ciarlet, Ronen Nazarian, Sara Tajyar and Benhur Lee

doi: 10.1038/nature03838

See also: Editor's summary


Regulation of Mycobacterium tuberculosis cell envelope composition and virulence by intramembrane proteolysis p406

Hideki Makinoshima and Michael S. Glickman

doi: 10.1038/nature03713

See also: Editor's summary


Trans-SNARE pairing can precede a hemifusion intermediate in intracellular membrane fusion p410

Christoph Reese, Felix Heise and Andreas Mayer

doi: 10.1038/nature03722


Structural basis of family-wide Rab GTPase recognition by rabenosyn-5 p415

Sudharshan Eathiraj, Xiaojing Pan, Christopher Ritacco and David G. Lambright

doi: 10.1038/nature03798


Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5 p420

Alessandra Picollo and Michael Pusch

doi: 10.1038/nature03720


Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins p424

Olaf Scheel, Anselm A. Zdebik, Stéphane Lourdel and Thomas J. Jentsch

doi: 10.1038/nature03860


SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase p428

Boris Pfander, George-Lucian Moldovan, Meik Sacher, Carsten Hoege and Stefan Jentsch

doi: 10.1038/nature03665


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Naturejobs

Prospect

A tangential route to success p435

Young scientist follows a bench tangent to biotech success

Paul Smaglik

doi:10.1038/nj7049-435a


Postdocs and Students

Learning to mentor p436

Having a good mentor can determine the direction and probability of success for a young researcher. But mentoring takes skill, and institutions are paying attention to their training, says Virginia Gewin.

Virginia Gewin

doi:10.1038/nj7049-436a


Career Views

Giovanni Galizia, professor of neurobiology, University of Konstanz, Germany p438

German scientist coming home from California

Giovanni Galizia

doi:10.1038/nj7049-438a


Scientists & Societies p438

Swedish scientists seek strength in numbers

Marita Teräs

doi:10.1038/nj7049-438b


Graduate Journal:  A study in time p438

Graduate experience warps time

Anne Margaret Lee

doi:10.1038/nj7049-438c


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Futures

Don't mention the 'F' word p440

Raising brows.

Neil Mathur

doi: 10.1038/436440a


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