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Editorials

Action, not words p151

Japan is beginning to recognize that the status and treatment of women researchers must change — but it has yet to take decisive action to address the problem.

doi: 10.1038/436151a


Two cheers for the G8 p151

World leaders made modest but welcome progress on poverty in Africa and climate change.

doi: 10.1038/436151b


Diversionary tactics p152

A map in a Nature supplement is being used to divert debate about science funding in China.

doi: 10.1038/436152a


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Research Highlights

Research highlights p154

doi: 10.1038/436154a


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News

Grim but determined — the G8 reaches accord on Africa and climate p156

Overshadowed by terror attacks in London, the G8 leaders remain focused at summit's close.

Declan Butler and Quirin Schiermeier

doi: 10.1038/436156a


Deep Impact: sifting through the debris p158

When Deep Impact's washing-machine-sized probe slammed into comet Tempel 1 on 4 July, teams of astronomers watched using telescopes in space and around the world. Nature investigates what the images tell us so far about the comet's composition and history.

Mark Peplow

doi: 10.1038/436158a


Rival monsoon forecasts banned p161

Storm over India's restrictions on rainfall predictions.

K. S. Jayaraman

doi: 10.1038/436161a


Sidelines p162

doi: 10.1038/436162a


Caveman DNA hints at map of migration p162

Oldest American genetic sample reveals early New World frontiers.

Rex Dalton

doi: 10.1038/436162b


Time to move on from shuttle, says astronaut p163

Tony Reichhardt talks to former spaceman George 'Pinky' Nelson about NASA's future.

doi: 10.1038/436163a


News in brief p164

doi: 10.1038/436164a


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News Features

Spray-on skin:  Hard graft p166

Surgeon Fiona Wood has pioneered a controversial treatment to reduce scarring in burns victims. Carina Dennis finds out how she counters her critics.

doi: 10.1038/436166a


Earth observing:  Something to watch over us p168

An ambitious international project to unite the planet's Earth-observing systems is under way. But getting everyone on board is no easy task, says Naomi Lubick.

doi: 10.1038/436168a

See also: Editor's summary


Nobel laureates:  Close encounters p170

After a low-key existence for more than 50 years, Germany's Lindau meetings have opened their doors to the world. Alison Abbott joined 44 Nobel laureates as they mingled with young scientists.

doi: 10.1038/436170a

See also: Editor's summary


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Business

Industry lured by the gains of going green p173

Global report highlights how ecology and the environment affect business.

Virginia Gewin

doi: 10.1038/436173a


In brief p173

doi: 10.1038/436173b


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Correspondence

Mysterious disappearance of female investigators p174

Darach Watson, Anja C. Andersen and Jens Hjorth

doi: 10.1038/436174a


Rising temperatures are likely to reduce crop yields p174

John R. Porter

doi: 10.1038/436174b


No royal road to protein structure determination p174

Luca Pellegrini

doi: 10.1038/436174c


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Commentary

When will we tame the oceans? p175

In fisheries across the world, fish stocks are declining fast. Future preservation and management of the ocean's resources will require a transformation of our relationship with the seas, argues John Marra.

doi: 10.1038/436175a

See also: Editor's summary


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Books and Arts

The Arctic paradox p177

The traditional diet of Inuits has health benefits but exposes them to dangerous levels of pollutants.

Geir Wing Gabrielsen reviews Silent Snow: The Slow Poisoning of the Arctic by Marla Cone

doi: 10.1038/436177a


Dissecting the right brain p178

Paul Bloom reviews The Ethical Brain by Michael S. Gazzaniga

doi: 10.1038/436178a


Science in culture p179

An art installation hints that, even in a forest, wind may disperse tree seeds farther than expected.

Henry S. Horn

doi: 10.1038/436179a


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News and Views

Developmental biology: Tiny brakes for a growing heart p181

The discovery of microRNAs has revolutionized many areas of biology. The latest news is that these RNAs seem to regulate the crucial balance between growth and specialization of cardiac cells.

Benoit G. Bruneau

doi: 10.1038/436181a

See also: Editor's summary


Astronomy:  Giant planet seeks nursery place p182

A further discovery of a planet in a binary star system — this time close in — could prove a problem for accepted theories of planetary formation. The implication is that there are more planets out there than we thought.

Artie P. Hatzes and Günther Wuchterl

doi: 10.1038/436182a

See also: Editor's summary


Evolutionary biology: Relativity for molecular clocks p183

An analysis of genetic data sets from primates and birds provides firm evidence that molecular evolution is faster on shorter than on longer timescales. The estimated times of various evolutionary events require a rethink.

David Penny

doi: 10.1038/436183a


Cancer biology:  Sleeping Beauty awakens p184

Ancient jumping DNA found napping in fish has been revived and is being used to identify cancer genes in mice. But the benefits of this aptly named 'Sleeping Beauty' system could reach far beyond cancer.

Keith C. Weiser and Monica J. Justice

doi: 10.1038/436184a

See also: Editor's summary


50 and 100 years ago p185

doi: 10.1038/436185a


Particle physics:  Weighty questions p186

In an unprecedented feat of computation, particle theorists made the most precise prediction yet of the mass of the 'charm−bottom' particle. Days later, experimentalists dramatically confirmed that prediction.

Ian Shipsey

doi: 10.1038/436186a


Physical chemistry:  Trapped gas p187

Acetylene is a gas with many industrial applications. A highly efficient method to separate it from its close relation, carbon dioxide, is a promising route for purifying and storing 'strategic' gases in general.

Gérard Férey

doi: 10.1038/436187a


Entomology:  Incompatible mosquitoes p189

Infection of mosquitoes by a particular bacterium has a fiendishly complicated influence on the success or failure of mosquito breeding. A window now opens on the molecular basis of this 'cytoplasmic incompatibility'.

Ary A. Hoffmann

doi: 10.1038/436189a

See also: Editor's summary


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Brief Communications

Avian flu:  H5N1 virus outbreak in migratory waterfowl p191

A worrying development could help to spread this dangerous virus beyond its stronghold in southeast Asia.

H. Chen, G. J. D. Smith, S. Y. Zhang, K. Qin, J. Wang, K. S. Li, R. G. Webster, J. S. M. Peiris and Y. Guan

doi: 10.1038/nature03974


Conservation:  Top predators and biodiversity p192

Fabrizio Sergio, Ian Newton and Luigi Marchesi

doi: 10.1038/436192a


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Review Article

Common mechanisms of nerve and blood vessel wiring p193

Peter Carmeliet and Marc Tessier-Lavigne

doi: 10.1038/nature03875

See also: Editor's summary


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Articles

Insight into the 2004 Sumatra−Andaman earthquake from GPS measurements in southeast Asia p201

C. Vigny, W. J. F. Simons, S. Abu, Ronnachai Bamphenyu, Chalermchon Satirapod, Nithiwatthn Choosakul, C. Subarya, A. Socquet, K. Omar, H. Z. Abidin and B. A. C. Ambrosius

doi: 10.1038/nature03937

See also: Editor's summary


Blimp1 is a critical determinant of the germ cell lineage in mice p207

Yasuhide Ohinata, Bernhard Payer, Dónal O'Carroll, Katia Ancelin, Yukiko Ono, Mitsue Sano, Sheila C. Barton, Tetyana Obukhanych, Michel Nussenzweig, Alexander Tarakhovsky, Mitinori Saitou and M. Azim Surani

doi: 10.1038/nature03813

See also: Editor's summary


Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis p214

Yong Zhao, Eva Samal and Deepak Srivastava

doi: 10.1038/nature03817

See also: Editor's summary | News and Views by Bruneau


Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system p221

Adam J. Dupuy, Keiko Akagi, David A. Largaespada, Neal G. Copeland and Nancy A. Jenkins

doi: 10.1038/nature03691

See also: Editor's summary | News and Views by Weiser & Justice


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Letters

The discovery of a galaxy-wide superwind from a young massive galaxy at redshift z 3 p227

R. J. Wilman, J. Gerssen, R. G. Bower, S. L. Morris, R. Bacon, P. T. de Zeeuw and R. L. Davies

doi: 10.1038/nature03718

See also: Editor's summary


An extrasolar giant planet in a close triple-star system p230

Maciej Konacki

doi: 10.1038/nature03856

See also: Editor's summary | News and Views by Hatzes & Wuchterl


A frequency comb in the extreme ultraviolet p234

Christoph Gohle, Thomas Udem, Maximilian Herrmann, Jens Rauschenberger, Ronald Holzwarth, Hans A. Schuessler, Ferenc Krausz and Theodor W. Hänsch

doi: 10.1038/nature03851

See also: Editor's summary


Highly controlled acetylene accommodation in a metal−organic microporous material p238

Ryotaro Matsuda, Ryo Kitaura, Susumu Kitagawa, Yoshiki Kubota, Rodion V. Belosludov, Tatsuo C. Kobayashi, Hirotoshi Sakamoto, Takashi Chiba, Masaki Takata, Yoshiyuki Kawazoe and Yoshimi Mita

doi: 10.1038/nature03852

See also: News and Views by Férey


Regional insolation forcing of late Quaternary climate change in the Southern Hemisphere p242

Marcus J. Vandergoes, Rewi M. Newnham, Frank Preusser, Chris H. Hendy, Thomas V. Lowell, Sean J. Fitzsimons, Alan G. Hogg, Haino Uwe Kasper and Christian Schlüchter

doi: 10.1038/nature03826

See also: Editor's summary


Trace-element fractionation in Hadean mantle generated by melt segregation from a magma ocean p246

Guillaume Caro, Bernard Bourdon, Bernard J. Wood and Alexandre Corgne

doi: 10.1038/nature03827


Multiple volcanic episodes of flood basalts caused by thermochemical mantle plumes p250

Shu-Chuan Lin and Peter E. van Keken

doi: 10.1038/nature03697


Basic avian pulmonary design and flow-through ventilation in non-avian theropod dinosaurs p253

Patrick M. O'Connor and Leon P. A. M. Claessens

doi: 10.1038/nature03716

See also: Editor's summary


Wolbachia variability and host effects on crossing type in Culex mosquitoes p257

Steven P. Sinkins, Thomas Walker, Amy R. Lynd, Andrew R. Steven, Ben L. Makepeace, H. Charles J. Godfray and Julian Parkhill

doi: 10.1038/nature03629

See also: Editor's summary | News and Views by Hoffmann


Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortex p261

Yi Zuo, Guang Yang, Elaine Kwon and Wen-Biao Gan

doi: 10.1038/nature03715

See also: Editor's summary


Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism p266

Stefano Pluchino, Lucia Zanotti, Barbara Rossi, Elena Brambilla, Linda Ottoboni, Giuliana Salani, Marianna Martinello, Alessandro Cattalini, Alessandra Bergami, Roberto Furlan, Giancarlo Comi, Gabriela Constantin and Gianvito Martino

doi: 10.1038/nature03889

See also: Editor's summary


Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse p272

Lara S. Collier, Corey M. Carlson, Shruthi Ravimohan, Adam J. Dupuy and David A. Largaespada

doi: 10.1038/nature03681

See also: Editor's summary | News and Views by Weiser & Justice


Gli3 and Plzf cooperate in proximal limb patterning at early stages of limb development p277

Maria Barna, Pier Paolo Pandolfi and Lee Niswander

doi: 10.1038/nature03801


An Arabidopsis hAT-like transposase is essential for plant development p282

Paul Bundock and Paul Hooykaas

doi: 10.1038/nature03667

See also: Editor's summary


A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum p285

Jennifer L. Garrison, Eric J. Kunkel, Ramanujan S. Hegde and Jack Taunton

doi: 10.1038/nature03821


Selective inhibition of cotranslational translocation of vascular cell adhesion molecule 1 p290

Jürgen Besemer, Hanna Harant, Shirley Wang, Berndt Oberhauser, Katharina Marquardt, Carolyn A. Foster, Erwin P. Schreiner, Jan E. de Vries, Christiane Dascher-Nadel and Ivan J. D. Lindley

doi: 10.1038/nature03670


A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response p294

Hiroshi Masumoto, David Hawke, Ryuji Kobayashi and Alain Verreault

doi: 10.1038/nature03714


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Naturejobs

Prospect

Reality check p299

Complaints about supervisors ring true — but strategies to deal with them differ

Paul Smaglik

doi:10.1038/nj7048-299a


Career Views

Harry Stylli, chief executive and president, Sequenom, San Diego, California p300

Entrepreneur charts course from pharma to biotech

Harry Stylli

doi:10.1038/nj7048-300a


Nuts & Bolts p300

Advice for dealing with constant change

Deb Koen

doi:10.1038/nj7048-300b


Graduate Journal:  The cost of moving abroad p300

Who supports mobility more, academia or industry?

Tobias Langenhan

doi:10.1038/nj7048-300c


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Futures

The chemistry between us p302

Highs and lows.

Laura Nelson

doi: 10.1038/436302a


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