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Nature 436, 183-184 (14 July 2005) | doi:10.1038/436183a; Published online 13 July 2005
Evolutionary biology: Relativity for molecular clocks
David Penny1
Abstract
An analysis of genetic data sets from primates and birds provides firm evidence that molecular evolution is faster on shorter than on longer timescales. The estimated times of various evolutionary events require a rethink.
The relative constancy of the rate at which DNA sequences evolve has been a treasured icon of molecular evolution for nearly 40 years. The occurrence of such a stochastic 'molecular clock' was initially quite unexpected, and was explained by Motoo Kimura1 by assuming that most changes to amino-acid and nucleotide sequences were neutral — "neither beneficial nor injurious", in Charles Darwin's prescient phrase.
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Evolutionary biology Relativity for molecular clocksNature News and Views (14 Jul 2005)