Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 436, 181-182 (14 July 2005) | doi:10.1038/436181a; Published online 13 July 2005
Open Innovation Challenges
-
Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
- More Challenges
- Powered by:
nature jobs
Tenure-track Faculty Positions
- University of Michigan
- Ann Arbor, Michigan, USA
Electrophysiologist
- TCG Lifesciences Ltd
- Kolkata India
Developmental biology: Tiny brakes for a growing heart
Benoit G. Bruneau1
Abstract
The discovery of microRNAs has revolutionized many areas of biology. The latest news is that these RNAs seem to regulate the crucial balance between growth and specialization of cardiac cells.
MicroRNAs (miRNAs for short) are tiny RNA molecules that downregulate protein production, either by inhibiting the translation of protein from messenger RNA or by promoting the degradation of mRNA1, 2. In plants, miRNAs have major influences on embryonic development, primarily by slowing down the production of proteins that regulate gene expression.
- Benoit G. Bruneau is in the Department of Cardiovascular Research and Developmental Biology, The Hospital for Sick Children, and the Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario M5G 1X8, Canada.
Email: bbruneau@sickkids.ca
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
microRNA detection comes of ageNature Methods News and Views (01 Jan 2006)
Cancer genomics Small RNAs with big impactsNature News and Views (09 Jun 2005)
RESEARCH
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesisNature Article (14 Jul 2005)
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiationNature Genetics Letter (01 Feb 2006)
See all 30 matches for Research