Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 435, 1169-1170 (30 June 2005) | doi:10.1038/4351169a; Published online 29 June 2005
Cancer biology: Summing up cancer stem cells
Brian J. P. Huntly1 & D. Gary Gilliland1
Abstract
Are current cancer drugs targeted at the wrong kinds of cells? A pioneering approach to the development of treatments uses a mathematical model to follow how different types of tumour cells respond to therapy.
In this issue, Michor and colleagues (Dynamics of chronic myeloid leukaemia)1 address the vexing problem that although many cancer drugs dramatically reduce the size of tumours, most cancers will eventually recur, often fatally. The authors model the dynamic changes in populations of cancer cells during treatment, and their data fit with the theory that there is a small population of cells — 'cancer stem cells' — that are ultimately responsible for the growth of tumours and are resistant to current therapies.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Targeted cancer treatment: resisting arrestNature Medicine News and Views (01 Oct 2006)
Neurobiology At the root of brain cancerNature News and Views (18 Nov 2004)
See all 3 matches for News And ViewsRESEARCH
Dynamics of chronic myeloid leukaemiaNature Letters to Editor (30 Jun 2005)
Reply: The long-term response to imatinib treatment of CMLBritish Journal of Cancer Letter
See all 30 matches for Research