Table of contents

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In praise of soft science p1003

'Hard' scientists should stop looking down their noses at social scientists, and instead share methods that could help them address pressing societal problems.

doi: 10.1038/4351003a

Not-so-deep impact p1003

Research assessment rests too heavily on the inflated status of the impact factor.

doi: 10.1038/4351003b

Toyota on a roll p1004

Japan's approach to industrial innovation may be out of fashion, but it still delivers the goods.

doi: 10.1038/4351004a


Research Highlights

Research highlights p1006

doi: 10.1038/4351006a



Drug targeting: is race enough? p1008

Pharmaceutical firms urged to look beyond race as first 'Personalized' drug is approved

Meredith Wadman

doi: 10.1038/4351008a

Trouble brews over contested trend in hurricanes p1008

Latest analysis suggests global warming will increase intensity of storms.

Quirin Schiermeier

doi: 10.1038/4351008b

China's chicken farmers under fire for antiviral abuse p1009

Bird flu virus develops resistance to common drug thanks to overuse.

David Cyranoski

doi: 10.1038/4351009a

Databases in peril p1010

Life-sciences databases are in crisis, say their operators, as funders keen to support exciting new projects lose interest in maintaining existing services. Nature investigates the scale of the problem.

Zeeya Merali and Jim Giles

doi: 10.1038/4351010a

Earth holds comet smash in its sights p1013

Wider astronomy community watches and awaits Deep Impact.

Tony Reichhardt

doi: 10.1038/4351013a

Sidelines p1014

doi: 10.1038/4351014a

Bill on deep-sea fish farms brings wave of disapproval p1014

US government in deep water over plan to bring marine aquaculture within federal control.

Rex Dalton

doi: 10.1038/4351014b

Retracted papers damage work on DNA repair p1015

Colleagues in field left to 'start from scratch'

Erika Check

doi: 10.1038/4351015a

News in brief p1016

doi: 10.1038/4351016a


News Features

A trip of a lifetime p1018

Are research expeditions to far-flung destinations as glamorous as they sound? Amanda Haag joins a few research novices who gave up their holidays for science.

doi: 10.1038/4351018a

See also: Editor's summary

Back to our roots p1022

It was cold and clammy, but it changed the rules of life for ever. Helen Pilcher goes in search of the ancestor of all animals.

doi: 10.1038/4351022a

See also: Editor's summary

Dalton Conley profile:  Harder than Rocket Science p1024

Dalton Conley is an award-winning researcher who works on the politically charged issues of race, gender and class. He tells Tony Reichhardt why he wants to stress the 'science' in the social sciences.

doi: 10.1038/4351024a



Toyota's production line leads from lab to road p1026

Sparks of inspiration and close relations with group companies keep Toyota's central research labs motoring along, as Ichiko Fuyuno reports.

doi: 10.1038/4351026a

In brief p1027

doi: 10.1038/4351027a

Market watch p1027

doi: 10.1038/4351027b



Turkish research council is proud of its independence p1028

Nüket Yetis

doi: 10.1038/4351028a

No political agenda in academic bill of rights p1028

Sara Dogan

doi: 10.1038/4351028b

Sale of public databases puts biological data at risk p1028

A. Jamie Cuticchia and Gregg W. Silk

doi: 10.1038/4351028c


Books and Arts

Switching on evolution p1029

How does evo−devo explain the huge diversity of life on Earth?

Jerry A. Coyne reviews Endless Forms Most Beautiful: The New Science of Evo Devo by Sean B. Carroll

doi: 10.1038/4351029a

Exhibition:  Fresh flowers p1030

Colin Martin

doi: 10.1038/4351030a

See also: Editor's summary

Flood warnings p1031

Christer Nilsson reviews The Future of Large Dams: Dealing with the Social, Environmental and Political Costs by Thayer Scudder

doi: 10.1038/4351031a



Dynamic Universe p1033

The first person to carry out a modern survey of the night sky, Fritz Zwicky's astronomical observations led to a new picture of a turbulent Universe that is punctuated by violent events.

Freeman Dyson

doi: 10.1038/4351033a


News and Views

Low-temperature physics:  A quantum revolution p1035

Tiny quantum tornadoes observed in ultracold gases of fermionic atoms provide definitive evidence of superfluidity, and open up new vistas in the modelling of quantum many-body systems.

Rudolf Grimm

doi: 10.1038/4351035a

See also: Editor's summary

Neuroscience:  Friends and grandmothers p1036

How do neurons in the brain represent movie stars, famous buildings and other familiar objects? Rare recordings from single neurons in the human brain provide a fresh perspective on the question.

Charles E. Connor

doi: 10.1038/4351036a

See also: Editor's summary

Earth science:  New Madrid in motion p1037

A new network of geodetic field stations has greatly improved monitoring of relative motion across a seismic zone in the central United States. It seems that rapid deformation is occurring across this fault system.

Martitia P. Tuttle

doi: 10.1038/4351037a

See also: Editor's summary

50 and 100 years ago p1038

doi: 10.1038/4351038a

Evolutionary biology:  Island of the clones p1039

The discovery of an all-female population of damselflies in the Azores archipelago provides a novelty for entomologists. It also highlights the unique selection pressures faced by species that colonize islands.

Thomas N. Sherratt and Christopher D. Beatty

doi: 10.1038/4351039a

Consciousness:  Crick and the claustrum p1040

Francis Crick believed that, in biology, structure is the natural path to understanding function. In his later career, he applied this dictum to the study of consciousness.

Charles F. Stevens

doi: 10.1038/4351040a

Animal behaviour:  Congo's art p1040

Tim Lincoln

doi: 10.1038/4351040b

Granular matter:  A tale of tails p1041

Granular materials such as sand can either be jammed and rigid, or yield and flow. Puzzling changes in the forces between the grains deepen the mystery surrounding this basic, but poorly understood, transition.

Martin van Hecke

doi: 10.1038/4351041a

Neuroscience:  An intrusive chaperone p1042

Stargazin is best known for helping to ferry receptor proteins to the surface of neurons. The discovery that it has an unexpected additional role has widespread implications for the way that neurons talk to each other.

Anders S. Kristensen and Stephen F. Traynelis

doi: 10.1038/4351042a

See also: Editor's summary

Obituary:  Fred S. Rosen (1930−2005) p1044

Immunologist, paediatrician and polymath

Walter Gratzer and David G. Nathan

doi: 10.1038/4351044a


Brief Communications

Surface tension:  Floater clustering in a standing wave p1045

Capillarity effects drive hydrophilic or hydrophobic particles to congregate at specific points on a wave.

G. Falkovich, A. Weinberg, P. Denissenko and S. Lukaschuk

doi: 10.1038/4351045a

Biodiversity:  Disease threat to European fish p1046

Rodolphe E. Gozlan, Sophie St-Hilaire, Stephen W. Feist, Paul Martin and Michael L. Kent

doi: 10.1038/4351046a

See also: Editor's summary


Brief Communications Arising

Plant communities:  Ecosystem stability in Inner Mongolia pE5

Shiping Wang, Haishan Niu, Xiaoyong Cui, Shu Jiang, Yonghong Li, Xiangming Xiao, Jinzhi Wang, Guojie Wang, Dehua Huang, Qiuhui Qi and Zonggui Yang

doi: 10.1038/nature03862

Plant communities:  Ecosystem maturity and performance pE6

Qinfeng Guo

doi: 10.1038/nature03583

Plant communities:  Ecosystem stability in Inner Mongolia (reply) pE6

Jianguo Wu, Yongfei Bai, Xingguo Han, Linghao Li and Zuozhong Chen

doi: 10.1038/nature03584



Vortices and superfluidity in a strongly interacting Fermi gas p1047

M. W. Zwierlein, J. R. Abo-Shaeer, A. Schirotzek, C. H. Schunck and W. Ketterle

doi: 10.1038/nature03858

See also: Editor's summary | News and Views by Grimm

Stargazin modulates AMPA receptor gating and trafficking by distinct domains p1052

Susumu Tomita, Hillel Adesnik, Masayuki Sekiguchi, Wei Zhang, Keiji Wada, James R. Howe, Roger A. Nicoll and David S. Bredt

doi: 10.1038/nature03624

See also: Editor's summary | News and Views by Kristensen & Traynelis

A structural basis for allosteric control of DNA recombination by lambda integrase p1059

Tapan Biswas, Hideki Aihara, Marta Radman-Livaja, David Filman, Arthur Landy and Tom Ellenberger

doi: 10.1038/nature03657



A planetary system as the origin of structure in Fomalhaut's dust belt p1067

Paul Kalas, James R. Graham and Mark Clampin

doi: 10.1038/nature03601

See also: Editor's summary

Timescales of shock processes in chondritic and martian meteorites p1071

P. Beck, Ph. Gillet, A. El Goresy and S. Mostefaoui

doi: 10.1038/nature03616

See also: Editor's summary

Structural signature of jamming in granular media p1075

Eric I. Corwin, Heinrich M. Jaeger and Sidney R. Nagel

doi: 10.1038/nature03698

See also: News and Views by van Hecke

Contact force measurements and stress-induced anisotropy in granular materials p1079

T. S. Majmudar and R. P. Behringer

doi: 10.1038/nature03805

See also: News and Views by van Hecke

Astronomical pacing of late Palaeocene to early Eocene global warming events p1083

Lucas J. Lourens, Appy Sluijs, Dick Kroon, James C. Zachos, Ellen Thomas, Ursula Röhl, Julie Bowles and Isabella Raffi

doi: 10.1038/nature03814

Space geodetic evidence for rapid strain rates in the New Madrid seismic zone of central USA p1088

R. Smalley, Jr, M. A. Ellis, J. Paul and R. B. Van Arsdale

doi: 10.1038/nature03642

See also: Editor's summary | News and Views by Tuttle

First evidence of a venom delivery apparatus in extinct mammals p1091

Richard C. Fox and Craig S. Scott

doi: 10.1038/nature03646

See also: Editor's summary

Aerodynamics of the hovering hummingbird p1094

Douglas R. Warrick, Bret W. Tobalske and Donald R. Powers

doi: 10.1038/nature03647

See also: Editor's summary

Extracellular electron transfer via microbial nanowires p1098

Gemma Reguera, Kevin D. McCarthy, Teena Mehta, Julie S. Nicoll, Mark T. Tuominen and Derek R. Lovley

doi: 10.1038/nature03661

See also: Editor's summary

Invariant visual representation by single neurons in the human brain p1102

R. Quian Quiroga, L. Reddy, G. Kreiman, C. Koch and I. Fried

doi: 10.1038/nature03687

See also: Editor's summary | News and Views by Connor

An endocannabinoid mechanism for stress-induced analgesia p1108

Andrea G. Hohmann, Richard L. Suplita, Nathan M. Bolton, Mark H. Neely, Darren Fegley, Regina Mangieri, Jocelyn F. Krey, J. Michael Walker, Philip V. Holmes, Jonathon D. Crystal, Andrea Duranti, Andrea Tontini, Marco Mor, Giorgio Tarzia and Daniele Piomelli

doi: 10.1038/nature03658

See also: Editor's summary

Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function p1113

Marie Kmita, Basile Tarchini, Jozsef Zàkàny, Malcolm Logan, Clifford J. Tabin and Denis Duboule

doi: 10.1038/nature03648

Abnormal display of PfEMP-1 on erythrocytes carrying haemoglobin C may protect against malaria p1117

Rick M. Fairhurst, Dror I. Baruch, Nathaniel J. Brittain, Graciela R. Ostera, John S. Wallach, Holly L. Hoang, Karen Hayton, Aldiouma Guindo, Morris O. Makobongo, Owen M. Schwartz, Anatole Tounkara, Ogobara K. Doumbo, Dapa A. Diallo, Hisashi Fujioka, May Ho and Thomas E. Wellems

doi: 10.1038/nature03631

See also: Editor's summary

R gene expression induced by a type-III effector triggers disease resistance in rice p1122

Keyu Gu, Bing Yang, Dongsheng Tian, Lifang Wu, Dongjiang Wang, Chellamma Sreekala, Fan Yang, Zhaoqing Chu, Guo-Liang Wang, Frank F. White and Zhongchao Yin

doi: 10.1038/nature03630

EphB receptor activity suppresses colorectal cancer progression p1126

Eduard Batlle, Julinor Bacani, Harry Begthel, Suzanne Jonkeer, Alexander Gregorieff, Maaike van de Born, Núria Malats, Elena Sancho, Elles Boon, Tony Pawson, Steven Gallinger, Steven Pals and Hans Clevers

doi: 10.1038/nature03626

See also: Editor's summary




Fixing a broken record p1131

Visualizing 'career space' can help you navigate more easily between disciplines, sectors and job function

Paul Smaglik

doi: 10.1038/nj7045-1131a

Special Report

Picture this p1132

Buoyed by a range of new technologies, science illustration is expanding its remit to offer careers beyond publishing in areas such as advertising and law. Virginia Gewin reports.

Virginia Gewin

doi: 101.1038/nj7045-1132a



Omphalosphere: New York 2057 p1136

A trip to the Zoo, a visit to the Library.

Jack Cohen

doi: 10.1038/4351136a

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