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Nature 435, 891-893 (16 June 2005) | doi:10.1038/435891a; Published online 15 June 2005
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Professor of Microscopy (W2)
- Friedrich-Schiller-University
- Jena Germany
Head of Formulation R&D
- Syngene International Limited
- Bangalore 560 099 India
Malaria: Fungal allies enlisted
Yannis Michalakis1 & François Renaud1
Abstract
The mosquito-killing capabilities of fungi can in principle be deployed in the fight against malaria. But long experience of unfulfilled hopes in this complex arena shows the need to proceed cautiously.
Many malaria control measures have centred on the mosquito vector of the Plasmodium parasite that causes the disease. Female mosquitoes transmit Plasmodium from human to human after feeding on the blood of an infected person — hence the age-old use of bednets, and the more recent attempts to genetically manipulate mosquitoes to make them resistant to parasite infection, or to reduce mosquito populations with insecticides.
- Yannis Michalakis and François Renaud are in the Laboratoire de Génétique et Evolution des Maladies Infectieuses, UMR CNRS IRD 2724, IRD, 911 Avenue Agropolis, 34394 Montpellier Cedex 5, France.
Email: Yannis.Michalakis@mpl.ird.fr
Email: Francois.Renaud@mpl.ird.fr
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