FIGURE 1. MicroRNA expression profiling of P493-6 cells with high and low c-Myc expression.
From the following article:
c-Myc-regulated microRNAs modulate E2F1 expression
Kathryn A. O'Donnell, Erik A. Wentzel, Karen I. Zeller, Chi V. Dang and Joshua T. Mendell
Nature 435, 839-843(9 June 2005)
doi:10.1038/nature03677

a, Western blot analysis of c-Myc in untreated cells or in cells treated with tetracycline (Tet). Blots were stripped and reprobed for
-tubulin to demonstrate equal loading of samples. b, MicroRNA expression arrays hybridized with RNA from tet-treated (+ Tet) or untreated (- Tet) cells. Magnified panels show miRNAs that were consistently upregulated in the high c-Myc state. A probe complementary to threonine tRNA (tRNAThr) served as a control for equal hybridization.
