Supplementary information
From the following article:
Interchromosomal associations between alternatively expressed loci
Charalampos G. Spilianakis, Maria D. Lalioti, Terrence Town, Gap Ryol Lee & Richard A. Flavell
Nature 435, 637-645(2 June 2005)
doi:10.1038/nature03574
Supplementary Figure S1
The IFN-
and TH2 loci are colocalized in the nucleus as detected by two dimensional-fluorescence in situ hybridization
Supplementary Figure S2
Immuno-DNA FISH experiments reveal that the colocalized signals reside in euchromatin
Supplementary Figure S3 xm-repla ce_text {title}
Digestion of chromatinized genomic DNA within the nuclei of different cells types.
Supplementary Figure S3 xm-repla ce_text {title} - Download PowerPoint (79KB)
Supplementary Figure S4
IFN
and TH2 loci colocalize in a more loose manner in the T cell nucleus.
Supplementary Figure Legends
Legends to accompany the above Supplementary Information
Supplementary Methods
Additional descripton of the methods used in this study, including Chromosome conformation capture analysis.
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