Supplementary information

From the following article:

Interchromosomal associations between alternatively expressed loci

Charalampos G. Spilianakis, Maria D. Lalioti, Terrence Town, Gap Ryol Lee & Richard A. Flavell

Nature 435, 637-645(2 June 2005)

doi:10.1038/nature03574

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Supplementary Figure S1

The IFN-gamma and TH2 loci are colocalized in the nucleus as detected by two dimensional-fluorescence in situ hybridization

Supplementary Figure S2

Immuno-DNA FISH experiments reveal that the colocalized signals reside in euchromatin

Supplementary Figure S3 xm-repla ce_text {title}

Digestion of chromatinized genomic DNA within the nuclei of different cells types.

Supplementary Figure S4

IFNgamma and TH2 loci colocalize in a more loose manner in the T cell nucleus.

Supplementary Figure Legends

Legends to accompany the above Supplementary Information

Supplementary Methods

Additional descripton of the methods used in this study, including Chromosome conformation capture analysis.

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