Highly efficient endogenous human gene correction using designed zinc-finger nucleases

doi:doi:10.1038/nature03556

From the following article:

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

Fyodor D. Urnov, Jeffrey C. Miller, Ya-Li Lee, Christian M. Beausejour, Jeremy M. Rock, Sheldon Augustus, Andrew C. Jamieson, Matthew H. Porteus, Philip D. Gregory & Michael C. Holmes

Nature 435, 646-651(2 June 2005)

doi:10.1038/nature03556

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Supplementary Figures S1-S5

Contains Supplementary Figures and accompanying Supplementary Figure Legends

Supplementary Figures S1-S5 - Download Word file (988KB)

Supplementary Notes

Narrative for Supplementary Figures S2 and S3.

Supplementary Notes - Download Word file (30KB)

Supplementary Methods

Includes details of donor plasmid generation, tissue culture procedures, PCR-based assay for gene correction at gamma C and quantitative RT-PCR, and Western blot assays for gamma C.