Provider: Nature Publishing Group Content: application/x-research-info-systems TY - JOUR AU - Wallar, B. J. AU - Alberts, A. S. TI - The formins: active scaffolds that remodel the cytoskeleton JO - Trends Cell Biol. PY - 2003/// VL - 13 SP - 435 EP - 446 M3 - 10.1016/S0962-8924(03)00153-3 N1 - 10.1016/S0962-8924(03)00153-3 UR - http://dx.doi.org/10.1016/S0962-8924(03)00153-3 ER - TY - JOUR AU - Zigmond, S. H. TI - Formin-induced nucleation of actin filaments JO - Curr. Opin. Cell Biol. PY - 2004/// VL - 16 SP - 99 EP - 105 M3 - 10.1016/j.ceb.2003.10.019 N1 - 10.1016/j.ceb.2003.10.019 UR - http://dx.doi.org/10.1016/j.ceb.2003.10.019 ER - TY - JOUR AU - Alberts, A. S. TI - Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain JO - J. Biol. Chem. PY - 2001/// VL - 276 SP - 2824 EP - 2830 M3 - 10.1074/jbc.M006205200 N1 - 10.1074/jbc.M006205200 UR - http://dx.doi.org/10.1074/jbc.M006205200 ER - TY - JOUR AU - Watanabe, N. AU - Kato, T. AU - Fujita, A. AU - Ishizaki, T. AU - Narumiya, S. TI - Cooperation between mDia1 and ROCK in Rho-induced actin reorganization JO - Nature Cell Biol. PY - 1999/// VL - 1 SP - 136 EP - 143 M3 - 10.1038/11056 N1 - 10.1038/11056 UR - http://dx.doi.org/10.1038/11056 ER - TY - JOUR AU - Pruyne, D. TI - Role of formins in actin assembly: nucleation and barbed-end association JO - Science PY - 2002/// VL - 297 SP - 531 EP - 532 M3 - 10.1126/science.1074649 N1 - 10.1126/science.1074649 UR - http://dx.doi.org/10.1126/science.1074649 ER - TY - JOUR AU - Sagot, I. AU - Rodal, A. A. AU - Moseley, J. AU - Goode, B. L. AU - Pellmann, D. TI - An actin nucleation mechanism mediated by Bni1 and profilin JO - Nature Cell Biol. PY - 2002/// VL - 4 SP - 626 EP - 631 M3 - 10.1038/ncb834 N1 - 10.1038/ncb834 UR - http://dx.doi.org/10.1038/ncb834 ER - TY - JOUR AU - Kovar, D. R. AU - Kuhn, J. R. AU - Tichy, A. L. AU - Pollard, T. D. TI - The fission yeast cytokinesis formin Cdc12p is a barbed end actin filament capping protein gated by profilin JO - J. Cell Biol. PY - 2003/// VL - 161 SP - 875 EP - 887 M3 - 10.1083/jcb.200211078 N1 - 10.1083/jcb.200211078 UR - http://dx.doi.org/10.1083/jcb.200211078 ER - TY - JOUR AU - Li, F. AU - Higgs, H. N. TI - The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition JO - Curr. Biol. PY - 2003/// VL - 13 SP - 1335 EP - 1340 M3 - 10.1016/S0960-9822(03)00540-2 N1 - 10.1016/S0960-9822(03)00540-2 UR - http://dx.doi.org/10.1016/S0960-9822(03)00540-2 ER - TY - JOUR AU - Shimada, A. TI - The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization JO - Mol. Cell PY - 2004/// VL - 13 SP - 511 EP - 522 M3 - 10.1016/S1097-2765(04)00059-0 N1 - 10.1016/S1097-2765(04)00059-0 UR - http://dx.doi.org/10.1016/S1097-2765(04)00059-0 ER - TY - JOUR AU - Xu, Y. TI - Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture JO - Cell PY - 2004/// VL - 116 SP - 711 EP - 723 M3 - 10.1016/S0092-8674(04)00210-7 N1 - 10.1016/S0092-8674(04)00210-7 UR - http://dx.doi.org/10.1016/S0092-8674(04)00210-7 ER - TY - JOUR AU - Zigmond, S. H. TI - Formin leaky cap allows elongation in the presence of tight capping proteins JO - Curr. Biol. PY - 2003/// VL - 13 SP - 1820 EP - 1823 M3 - 10.1016/j.cub.2003.09.057 N1 - 10.1016/j.cub.2003.09.057 UR - http://dx.doi.org/10.1016/j.cub.2003.09.057 ER - TY - JOUR AU - Kato, T. TI - Localization of a mammalian homolog of diaphanous, mDia1, to the mitotic spindle in HeLa cells JO - J. Cell Sci. PY - 2001/// VL - 114 SP - 775 EP - 784 ER - TY - JOUR AU - Etienne-Manneville, S. AU - Hall, A. TI - Rho GTPases in cell biology JO - Nature PY - 2002/// VL - 420 SP - 629 EP - 635 M3 - 10.1038/nature01148 N1 - 10.1038/nature01148 UR - http://dx.doi.org/10.1038/nature01148 ER - TY - JOUR AU - Nakano, K. TI - Distinct actions and cooperative roles of ROCK and mDia in Rho small G protein-induced reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells JO - Mol. Biol. Cell PY - 1999/// VL - 10 SP - 2481 EP - 2491 ER - TY - JOUR AU - Watanabe, N. TI - p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin JO - EMBO J. PY - 1997/// VL - 16 SP - 3044 EP - 3056 M3 - 10.1093/emboj/16.11.3044 N1 - 10.1093/emboj/16.11.3044 UR - http://dx.doi.org/10.1093/emboj/16.11.3044 ER - TY - JOUR AU - Gasman, S. AU - Kalaidzidis, Y. AU - Zerial, M. TI - RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase JO - Nature Cell Biol. PY - 2003/// VL - 5 SP - 195 EP - 204 M3 - 10.1038/ncb935 N1 - 10.1038/ncb935 UR - http://dx.doi.org/10.1038/ncb935 ER - TY - JOUR AU - Peng, J. AU - Wallar, B. J. AU - Flanders, A. AU - Swiatek, P. J. AU - Alberts, A. S. TI - Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42 JO - Curr. Biol. PY - 2003/// VL - 13 SP - 534 EP - 545 M3 - 10.1016/S0960-9822(03)00170-2 N1 - 10.1016/S0960-9822(03)00170-2 UR - http://dx.doi.org/10.1016/S0960-9822(03)00170-2 ER - TY - JOUR AU - Blumenstein, L. AU - Ahmadian, M. R. TI - Models of the cooperative mechanism for Rho-effector recognition: Implications for RhoA-mediated effector activation JO - J. Biol. Chem. PY - 2004/// VL - 279 SP - 53419 EP - 53426 M3 - 10.1074/jbc.M409551200 N1 - 10.1074/jbc.M409551200 UR - http://dx.doi.org/10.1074/jbc.M409551200 ER - TY - JOUR AU - Herrmann, C. AU - Horn, G. AU - Spaargaren, M. AU - Wittinghofer, A. TI - Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor JO - J. Biol. Chem. PY - 1996/// VL - 271 SP - 6794 EP - 6800 M3 - 10.1074/jbc.271.36.21848 N1 - 10.1074/jbc.271.36.21848 UR - http://dx.doi.org/10.1074/jbc.271.36.21848 ER - TY - JOUR AU - Krebs, A. AU - Rothkegel, M. AU - Klar, M. AU - Jockusch, B. M. TI - Characterization of functional domains of mDia1, a link between the small GTPase Rho and the actin cytoskeleton JO - J. Cell Sci. PY - 2001/// VL - 114 SP - 3663 EP - 3672 ER - TY - JOUR AU - Li, F. AU - Higgs, H. N. TI - Dissecting requirements for auto-inhibition of actin nucleation by the formin, mDia1 JO - J. Biol. Chem. PY - 2005/// VL - 280 SP - 6986 EP - 6992 M3 - 10.1074/jbc.M411605200 N1 - 10.1074/jbc.M411605200 UR - http://dx.doi.org/10.1074/jbc.M411605200 ER - TY - JOUR AU - Rose, R. AU - Wittinghofer, A. AU - Weyand, M. TI - The purification and crystallization of mDia1 in complex with RhoC JO - Acta Crystallogr. F PY - 2005/// VL - 61 SP - 225 EP - 227 ER - TY - JOUR AU - Huber, A. H. AU - Nelson, W. J. AU - Weis, W. I. TI - Three-dimensional structure of the armadillo repeat region of [beta]-catenin JO - Cell PY - 1997/// VL - 90 SP - 871 EP - 882 M3 - 10.1016/S0092-8674(00)80352-9 N1 - 10.1016/S0092-8674(00)80352-9 UR - http://dx.doi.org/10.1016/S0092-8674(00)80352-9 ER - TY - JOUR AU - Dvorsky, R. AU - Blumenstein, L. AU - Vetter, I. R. AU - Ahmadian, M. R. TI - Structural insights into the interaction of ROCKI with the switch regions of RhoA JO - J. Biol. Chem. PY - 2004/// VL - 279 SP - 7098 EP - 7104 M3 - 10.1074/jbc.M311911200 N1 - 10.1074/jbc.M311911200 UR - http://dx.doi.org/10.1074/jbc.M311911200 ER - TY - JOUR AU - Maesaki, R. TI - The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1 JO - Mol. Cell PY - 1999/// VL - 4 SP - 793 EP - 803 M3 - 10.1016/S1097-2765(00)80389-5 N1 - 10.1016/S1097-2765(00)80389-5 UR - http://dx.doi.org/10.1016/S1097-2765(00)80389-5 ER - TY - JOUR AU - Vetter, I. R. AU - Wittinghofer, A. TI - The guanine nucleotide-binding switch in three dimensions JO - Science PY - 2001/// VL - 294 SP - 1299 EP - 1304 M3 - 10.1126/science.1062023 N1 - 10.1126/science.1062023 UR - http://dx.doi.org/10.1126/science.1062023 ER - TY - JOUR AU - Shimizu, T. TI - An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RhoA complexed with GDP. Implications for the GDP/GTP exchange mechanism JO - J. Biol. Chem. PY - 2000/// VL - 275 SP - 18311 EP - 18317 M3 - 10.1074/jbc.M910274199 N1 - 10.1074/jbc.M910274199 UR - http://dx.doi.org/10.1074/jbc.M910274199 ER - TY - JOUR AU - Sahai, E. AU - Alberts, A. S. AU - Treisman, R. TI - RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation JO - EMBO J. PY - 1998/// VL - 17 SP - 1350 EP - 1361 M3 - 10.1093/emboj/17.5.1350 N1 - 10.1093/emboj/17.5.1350 UR - http://dx.doi.org/10.1093/emboj/17.5.1350 ER - TY - JOUR AU - Ehresmann, B. AU - Imbault, P. AU - Weil, J. H. TI - Spectrophotometric determination of protein concentration in cell extracts containing tRNA's and rRNA's JO - Anal. Biochem. PY - 1973/// VL - 54 SP - 454 EP - 463 M3 - 10.1016/0003-2697(73)90374-6 N1 - 10.1016/0003-2697(73)90374-6 UR - http://dx.doi.org/10.1016/0003-2697(73)90374-6 ER - TY - JOUR AU - Rittinger, K. TI - Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP JO - Nature PY - 1997/// VL - 388 SP - 693 EP - 697 M3 - 10.1038/41805 N1 - 10.1038/41805 UR - http://dx.doi.org/10.1038/41805 ER -