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Nature 435, 360-364 (19 May 2005) | doi:10.1038/nature03595;
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The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours
In mice, the Ter mutation causes primordial germ cell (PGC) loss in all genetic backgrounds. Ter is also a potent modifier of spontaneous testicular germ cell tumour (TGCT) susceptibility in the 129 family of inbred strains, and markedly increases TGCT incidence in 129-Ter/Ter males.
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