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Nature 435, 288-289 (19 May 2005) | doi:10.1038/435288a; Published online 18 May 2005

Neuroscience:  Plasticity and its limits

Martin I. Sereno1

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How much can the adult brain compensate for injury to the senses of touch or vision, for example? The answer from the latest results on the visual system, involving damage to the retina, seems to be 'very little'.

Many sensory systems are characterized by connections from receptor surfaces, such as the retina or skin, in which the relationship between neighbouring inputs is preserved. The resulting 'topological maps' are also commonly maintained in subsequent projections between sensory areas within the brain.

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